Cellular immune responses induced with dose-sparing intradermal administration of HIV vaccine to HIV-uninfected volunteers in the ANRS VAC16 trial.

Cellular immune responses induced with dose-sparing intradermal administration of HIV vaccine to HIV-uninfected volunteers in the ANRS VAC16 trial.

The objective was to compare the safety and cellular immunogenicity of intradermal versus intramuscular immunization with an HIV-lipopeptide candidate vaccine (LIPO-4) in healthy volunteers.A randomized, open-label trial with 24 weeks of follow-up was conducted in France at six HIV-vaccine trial sit...

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Main Authors: Odile Launay, Christine Durier, Corinne Desaint, Benjamin Silbermann, Angela Jackson, Gilles Pialoux, Bénédicte Bonnet, Isabelle Poizot-Martin, Gustavo Gonzalez-Canali, Lise Cuzin, Suzanne Figuereido, Mathieu Surenaud, Nadine Ben Hamouda, Hanne Gahery, Jeannine Choppin, Dominique Salmon, Corinne Guérin, Isabelle Bourgault Villada, Jean-Gérard Guillet, ANRS VAC16 Study Group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1942115?pdf=render

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