The association of enchondromatosis with malignant transformed chondrosarcoma and ovarian juvenile granulosa cell tumor (Ollier disease)
Objective: Ovarian juvenile granulosa cell tumor has an interesting association with multiple enchondromatosis (Ollier disease and Maffucci syndrome) and should be considered a leading diagnosis when an ovarian mass is found in young patients with these conditions. Besides the association with nonsk...
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| Format: | Article |
| Language: | English |
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Elsevier
2017-04-01
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| Series: | Taiwanese Journal of Obstetrics & Gynecology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1028455917300505 |
| _version_ | 1818055081388408832 |
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| author | Andrea Burgetova Zdenek Matejovsky Michal Zikan Jiri Slama Pavel Dundr Petr Skapa Kamila Benkova David Cibula Daniela Fischerova |
| author_facet | Andrea Burgetova Zdenek Matejovsky Michal Zikan Jiri Slama Pavel Dundr Petr Skapa Kamila Benkova David Cibula Daniela Fischerova |
| author_sort | Andrea Burgetova |
| collection | DOAJ |
| description | Objective: Ovarian juvenile granulosa cell tumor has an interesting association with multiple enchondromatosis (Ollier disease and Maffucci syndrome) and should be considered a leading diagnosis when an ovarian mass is found in young patients with these conditions. Besides the association with nonskeletal malignancies, there is a high risk of malignant transformation of enchondroma in chondrosarcoma as was also the case in this instance.
Case Report: The report uses multiple images to document the representative and characteristic markers of multiple enchondromas in a 22-year-old patient with Ollier disease complicated by malignant transformation of chondrosarcoma and in whom the disease is associated with ovarian juvenile granulosa cell tumor of the right ovary.
Conclusion: It is important to recognize that when the female patient presents with enchondromatosis and a large unilateral multilocular-solid ovarian mass, the specific diagnosis of granulosa cell tumor can be made with high accuracy. |
| first_indexed | 2024-12-10T12:07:16Z |
| format | Article |
| id | doaj.art-c336388b861c47d68b6243c79210f2a5 |
| institution | Directory Open Access Journal |
| issn | 1028-4559 |
| language | English |
| last_indexed | 2024-12-10T12:07:16Z |
| publishDate | 2017-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Taiwanese Journal of Obstetrics & Gynecology |
| spelling | doaj.art-c336388b861c47d68b6243c79210f2a52022-12-22T01:49:26ZengElsevierTaiwanese Journal of Obstetrics & Gynecology1028-45592017-04-0156225325710.1016/j.tjog.2017.02.002The association of enchondromatosis with malignant transformed chondrosarcoma and ovarian juvenile granulosa cell tumor (Ollier disease)Andrea Burgetova0Zdenek Matejovsky1Michal Zikan2Jiri Slama3Pavel Dundr4Petr Skapa5Kamila Benkova6David Cibula7Daniela Fischerova8Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech RepublicOrthopedic Clinic, Bulovka Hospital, First Faculty of Medicine, Charles University, Czech RepublicGynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech RepublicGynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech RepublicDepartment of Pathology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech RepublicDepartment of Pathology, Second Faculty of Medicine, Charles University, Czech RepublicDepartment of Pathology, Bulovka Hospital, First Faculty of Medicine, Charles University, Czech RepublicGynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech RepublicGynecologic Oncology Center, Department of Obstetrics and Gynecology, First Faculty of Medicine, Charles University and General University Hospital in Prague, Czech RepublicObjective: Ovarian juvenile granulosa cell tumor has an interesting association with multiple enchondromatosis (Ollier disease and Maffucci syndrome) and should be considered a leading diagnosis when an ovarian mass is found in young patients with these conditions. Besides the association with nonskeletal malignancies, there is a high risk of malignant transformation of enchondroma in chondrosarcoma as was also the case in this instance. Case Report: The report uses multiple images to document the representative and characteristic markers of multiple enchondromas in a 22-year-old patient with Ollier disease complicated by malignant transformation of chondrosarcoma and in whom the disease is associated with ovarian juvenile granulosa cell tumor of the right ovary. Conclusion: It is important to recognize that when the female patient presents with enchondromatosis and a large unilateral multilocular-solid ovarian mass, the specific diagnosis of granulosa cell tumor can be made with high accuracy.http://www.sciencedirect.com/science/article/pii/S1028455917300505chondrosarcomaenchondromatosisjuvenile granulosa cell tumorOllier diseaseultrasound |
| spellingShingle | Andrea Burgetova Zdenek Matejovsky Michal Zikan Jiri Slama Pavel Dundr Petr Skapa Kamila Benkova David Cibula Daniela Fischerova The association of enchondromatosis with malignant transformed chondrosarcoma and ovarian juvenile granulosa cell tumor (Ollier disease) Taiwanese Journal of Obstetrics & Gynecology chondrosarcoma enchondromatosis juvenile granulosa cell tumor Ollier disease ultrasound |
| title | The association of enchondromatosis with malignant transformed chondrosarcoma and ovarian juvenile granulosa cell tumor (Ollier disease) |
| title_full | The association of enchondromatosis with malignant transformed chondrosarcoma and ovarian juvenile granulosa cell tumor (Ollier disease) |
| title_fullStr | The association of enchondromatosis with malignant transformed chondrosarcoma and ovarian juvenile granulosa cell tumor (Ollier disease) |
| title_full_unstemmed | The association of enchondromatosis with malignant transformed chondrosarcoma and ovarian juvenile granulosa cell tumor (Ollier disease) |
| title_short | The association of enchondromatosis with malignant transformed chondrosarcoma and ovarian juvenile granulosa cell tumor (Ollier disease) |
| title_sort | association of enchondromatosis with malignant transformed chondrosarcoma and ovarian juvenile granulosa cell tumor ollier disease |
| topic | chondrosarcoma enchondromatosis juvenile granulosa cell tumor Ollier disease ultrasound |
| url | http://www.sciencedirect.com/science/article/pii/S1028455917300505 |
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