Long Non-Coding RNAs in Liver Cancer and Nonalcoholic Steatohepatitis

This review aims to highlight the recent findings of long non-coding RNAs (lncRNAs) in liver disease. In particular, we focus on the functions of lncRNAs in hepatocellular carcinoma (HCC) and non-alcoholic steatohepatitis (NASH). We summarize the current research trend in lncRNAs and their potential...

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Main Authors: Shizuka Uchida, Sakari Kauppinen
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Non-Coding RNA
Subjects:
Online Access:https://www.mdpi.com/2311-553X/6/3/34
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author Shizuka Uchida
Sakari Kauppinen
author_facet Shizuka Uchida
Sakari Kauppinen
author_sort Shizuka Uchida
collection DOAJ
description This review aims to highlight the recent findings of long non-coding RNAs (lncRNAs) in liver disease. In particular, we focus on the functions of lncRNAs in hepatocellular carcinoma (HCC) and non-alcoholic steatohepatitis (NASH). We summarize the current research trend in lncRNAs and their potential as biomarkers and therapeutic targets for the treatment of HCC and NASH.
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spelling doaj.art-c337061b7fe1458cbeafb048beef82c52023-11-20T11:50:29ZengMDPI AGNon-Coding RNA2311-553X2020-08-01633410.3390/ncrna6030034Long Non-Coding RNAs in Liver Cancer and Nonalcoholic SteatohepatitisShizuka Uchida0Sakari Kauppinen1Cardiovascular Innovation Institute, University of Louisville School of Medicine, Louisville, KY 40202, USACenter for RNA Medicine, Aalborg University, DK-2450 Copenhagen SV, DenmarkThis review aims to highlight the recent findings of long non-coding RNAs (lncRNAs) in liver disease. In particular, we focus on the functions of lncRNAs in hepatocellular carcinoma (HCC) and non-alcoholic steatohepatitis (NASH). We summarize the current research trend in lncRNAs and their potential as biomarkers and therapeutic targets for the treatment of HCC and NASH.https://www.mdpi.com/2311-553X/6/3/34liverlncRNAmiRNAliver cancerHCCNASH
spellingShingle Shizuka Uchida
Sakari Kauppinen
Long Non-Coding RNAs in Liver Cancer and Nonalcoholic Steatohepatitis
Non-Coding RNA
liver
lncRNA
miRNA
liver cancer
HCC
NASH
title Long Non-Coding RNAs in Liver Cancer and Nonalcoholic Steatohepatitis
title_full Long Non-Coding RNAs in Liver Cancer and Nonalcoholic Steatohepatitis
title_fullStr Long Non-Coding RNAs in Liver Cancer and Nonalcoholic Steatohepatitis
title_full_unstemmed Long Non-Coding RNAs in Liver Cancer and Nonalcoholic Steatohepatitis
title_short Long Non-Coding RNAs in Liver Cancer and Nonalcoholic Steatohepatitis
title_sort long non coding rnas in liver cancer and nonalcoholic steatohepatitis
topic liver
lncRNA
miRNA
liver cancer
HCC
NASH
url https://www.mdpi.com/2311-553X/6/3/34
work_keys_str_mv AT shizukauchida longnoncodingrnasinlivercancerandnonalcoholicsteatohepatitis
AT sakarikauppinen longnoncodingrnasinlivercancerandnonalcoholicsteatohepatitis