Shine like gold and sparkle like glitter: Three cases of lipoid pneumonia
Lipoid pneumonia (LP) is an unwonted, mostly asymptomatic entity which has no classical radiological appearance. It can be endogenous or exogenous depending upon the type of exposure or underlying milieu. It simulates a number of infective and malignant respiratory conditions and can go undiagnosed...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-01-01
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| Series: | Respiratory Medicine Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213007121000423 |
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| author | Vishak Acharya Nikhil Victor Dsouza Saraswathy Sreeram Santosh P.V. Rai Basavaprabhu Achappa |
| author_facet | Vishak Acharya Nikhil Victor Dsouza Saraswathy Sreeram Santosh P.V. Rai Basavaprabhu Achappa |
| author_sort | Vishak Acharya |
| collection | DOAJ |
| description | Lipoid pneumonia (LP) is an unwonted, mostly asymptomatic entity which has no classical radiological appearance. It can be endogenous or exogenous depending upon the type of exposure or underlying milieu. It simulates a number of infective and malignant respiratory conditions and can go undiagnosed or delayed leading to morbidity and mortality. We put forward three cases that initially presented as classical pneumonia, but on further assessment and investigations were diagnosed to be LP. All the three cases manifested with symptoms of fever, productive cough and breathlessness. Chest Xray and CT scan were indicative of consolidation. Bronchoalveolar lavage (BAL) evinced lipid laden macrophages that stained positive with fat stains (Sudan IV and Oil Red O). Two cases were endogenous and one was exogenous type. LP, owing to its nonspecific clinical presentation and radiographic signs, needs a high index of suspicion, and a detailed clinical history for accurate diagnosis. Corroboration of lipid laden alveolar macrophages in BAL is the crux to the diagnosis. Hence, clinicians should be cognizant of this condition and rule out LP in cases of non-resolving pneumonia in an appropriate clinical context. |
| first_indexed | 2024-12-22T13:54:33Z |
| format | Article |
| id | doaj.art-c3437e962a3f49de8416f92e7ec5dfbf |
| institution | Directory Open Access Journal |
| issn | 2213-0071 |
| language | English |
| last_indexed | 2024-12-22T13:54:33Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Respiratory Medicine Case Reports |
| spelling | doaj.art-c3437e962a3f49de8416f92e7ec5dfbf2022-12-21T18:23:35ZengElsevierRespiratory Medicine Case Reports2213-00712021-01-0133101380Shine like gold and sparkle like glitter: Three cases of lipoid pneumoniaVishak Acharya0Nikhil Victor Dsouza1Saraswathy Sreeram2Santosh P.V. Rai3Basavaprabhu Achappa4Department of Pulmonary Medicine, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, IndiaDepartment of Internal Medicine, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India; Corresponding author.Department of Pathology, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, IndiaDepartment of Radiodiagnosis, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, IndiaDepartment of Internal Medicine, Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, IndiaLipoid pneumonia (LP) is an unwonted, mostly asymptomatic entity which has no classical radiological appearance. It can be endogenous or exogenous depending upon the type of exposure or underlying milieu. It simulates a number of infective and malignant respiratory conditions and can go undiagnosed or delayed leading to morbidity and mortality. We put forward three cases that initially presented as classical pneumonia, but on further assessment and investigations were diagnosed to be LP. All the three cases manifested with symptoms of fever, productive cough and breathlessness. Chest Xray and CT scan were indicative of consolidation. Bronchoalveolar lavage (BAL) evinced lipid laden macrophages that stained positive with fat stains (Sudan IV and Oil Red O). Two cases were endogenous and one was exogenous type. LP, owing to its nonspecific clinical presentation and radiographic signs, needs a high index of suspicion, and a detailed clinical history for accurate diagnosis. Corroboration of lipid laden alveolar macrophages in BAL is the crux to the diagnosis. Hence, clinicians should be cognizant of this condition and rule out LP in cases of non-resolving pneumonia in an appropriate clinical context.http://www.sciencedirect.com/science/article/pii/S2213007121000423Lipoid pneumoniaCholesterol pneumoniaLipid laden macrophagesFat stainsBronchoalveolar lavage |
| spellingShingle | Vishak Acharya Nikhil Victor Dsouza Saraswathy Sreeram Santosh P.V. Rai Basavaprabhu Achappa Shine like gold and sparkle like glitter: Three cases of lipoid pneumonia Respiratory Medicine Case Reports Lipoid pneumonia Cholesterol pneumonia Lipid laden macrophages Fat stains Bronchoalveolar lavage |
| title | Shine like gold and sparkle like glitter: Three cases of lipoid pneumonia |
| title_full | Shine like gold and sparkle like glitter: Three cases of lipoid pneumonia |
| title_fullStr | Shine like gold and sparkle like glitter: Three cases of lipoid pneumonia |
| title_full_unstemmed | Shine like gold and sparkle like glitter: Three cases of lipoid pneumonia |
| title_short | Shine like gold and sparkle like glitter: Three cases of lipoid pneumonia |
| title_sort | shine like gold and sparkle like glitter three cases of lipoid pneumonia |
| topic | Lipoid pneumonia Cholesterol pneumonia Lipid laden macrophages Fat stains Bronchoalveolar lavage |
| url | http://www.sciencedirect.com/science/article/pii/S2213007121000423 |
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