Microfluidic High-Throughput Platforms for Discovery of Novel Materials

High-throughput screening is a potent technique to accelerate the discovery and development of new materials. By performing massive synthesis and characterization processes in parallel, it can rapidly discover materials with desired components, structures and functions. Among the various approaches...

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Main Authors: Peipei Zhou, Jinxu He, Lu Huang, Ziming Yu, Zhenning Su, Xuetao Shi, Jianhua Zhou
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/10/12/2514
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author Peipei Zhou
Jinxu He
Lu Huang
Ziming Yu
Zhenning Su
Xuetao Shi
Jianhua Zhou
author_facet Peipei Zhou
Jinxu He
Lu Huang
Ziming Yu
Zhenning Su
Xuetao Shi
Jianhua Zhou
author_sort Peipei Zhou
collection DOAJ
description High-throughput screening is a potent technique to accelerate the discovery and development of new materials. By performing massive synthesis and characterization processes in parallel, it can rapidly discover materials with desired components, structures and functions. Among the various approaches for high-throughput screening, microfluidic platforms have attracted increasing attention. Compared with many current strategies that are generally based on robotic dispensers and automatic microplates, microfluidic platforms can significantly increase the throughput and reduce the consumption of reagents by several orders of magnitude. In this review, we first introduce current advances of the two types of microfluidic high-throughput platforms based on microarrays and microdroplets, respectively. Then the utilization of these platforms for screening different types of materials, including inorganic metals, metal alloys and organic polymers are described in detail. Finally, the challenges and opportunities in this promising field are critically discussed.
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spelling doaj.art-c34a0ad013834f3fb11f6ac96a2b0b042023-11-21T00:49:00ZengMDPI AGNanomaterials2079-49912020-12-011012251410.3390/nano10122514Microfluidic High-Throughput Platforms for Discovery of Novel MaterialsPeipei Zhou0Jinxu He1Lu Huang2Ziming Yu3Zhenning Su4Xuetao Shi5Jianhua Zhou6Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou 510006, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou 510006, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou 510006, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou 510006, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou 510006, ChinaNational Engineering Research Centre for Tissue Restoration and Reconstruction, School of Material Science and Engineering, South China University of Technology, Guangzhou 510640, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou 510006, ChinaHigh-throughput screening is a potent technique to accelerate the discovery and development of new materials. By performing massive synthesis and characterization processes in parallel, it can rapidly discover materials with desired components, structures and functions. Among the various approaches for high-throughput screening, microfluidic platforms have attracted increasing attention. Compared with many current strategies that are generally based on robotic dispensers and automatic microplates, microfluidic platforms can significantly increase the throughput and reduce the consumption of reagents by several orders of magnitude. In this review, we first introduce current advances of the two types of microfluidic high-throughput platforms based on microarrays and microdroplets, respectively. Then the utilization of these platforms for screening different types of materials, including inorganic metals, metal alloys and organic polymers are described in detail. Finally, the challenges and opportunities in this promising field are critically discussed.https://www.mdpi.com/2079-4991/10/12/2514high-throughput platformsmaterials screeningmicroarraymicrofluidic dropletmicro/nano-structures
spellingShingle Peipei Zhou
Jinxu He
Lu Huang
Ziming Yu
Zhenning Su
Xuetao Shi
Jianhua Zhou
Microfluidic High-Throughput Platforms for Discovery of Novel Materials
Nanomaterials
high-throughput platforms
materials screening
microarray
microfluidic droplet
micro/nano-structures
title Microfluidic High-Throughput Platforms for Discovery of Novel Materials
title_full Microfluidic High-Throughput Platforms for Discovery of Novel Materials
title_fullStr Microfluidic High-Throughput Platforms for Discovery of Novel Materials
title_full_unstemmed Microfluidic High-Throughput Platforms for Discovery of Novel Materials
title_short Microfluidic High-Throughput Platforms for Discovery of Novel Materials
title_sort microfluidic high throughput platforms for discovery of novel materials
topic high-throughput platforms
materials screening
microarray
microfluidic droplet
micro/nano-structures
url https://www.mdpi.com/2079-4991/10/12/2514
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