Microfluidic High-Throughput Platforms for Discovery of Novel Materials
High-throughput screening is a potent technique to accelerate the discovery and development of new materials. By performing massive synthesis and characterization processes in parallel, it can rapidly discover materials with desired components, structures and functions. Among the various approaches...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-12-01
|
Series: | Nanomaterials |
Subjects: | |
Online Access: | https://www.mdpi.com/2079-4991/10/12/2514 |
_version_ | 1797544699498594304 |
---|---|
author | Peipei Zhou Jinxu He Lu Huang Ziming Yu Zhenning Su Xuetao Shi Jianhua Zhou |
author_facet | Peipei Zhou Jinxu He Lu Huang Ziming Yu Zhenning Su Xuetao Shi Jianhua Zhou |
author_sort | Peipei Zhou |
collection | DOAJ |
description | High-throughput screening is a potent technique to accelerate the discovery and development of new materials. By performing massive synthesis and characterization processes in parallel, it can rapidly discover materials with desired components, structures and functions. Among the various approaches for high-throughput screening, microfluidic platforms have attracted increasing attention. Compared with many current strategies that are generally based on robotic dispensers and automatic microplates, microfluidic platforms can significantly increase the throughput and reduce the consumption of reagents by several orders of magnitude. In this review, we first introduce current advances of the two types of microfluidic high-throughput platforms based on microarrays and microdroplets, respectively. Then the utilization of these platforms for screening different types of materials, including inorganic metals, metal alloys and organic polymers are described in detail. Finally, the challenges and opportunities in this promising field are critically discussed. |
first_indexed | 2024-03-10T14:04:15Z |
format | Article |
id | doaj.art-c34a0ad013834f3fb11f6ac96a2b0b04 |
institution | Directory Open Access Journal |
issn | 2079-4991 |
language | English |
last_indexed | 2024-03-10T14:04:15Z |
publishDate | 2020-12-01 |
publisher | MDPI AG |
record_format | Article |
series | Nanomaterials |
spelling | doaj.art-c34a0ad013834f3fb11f6ac96a2b0b042023-11-21T00:49:00ZengMDPI AGNanomaterials2079-49912020-12-011012251410.3390/nano10122514Microfluidic High-Throughput Platforms for Discovery of Novel MaterialsPeipei Zhou0Jinxu He1Lu Huang2Ziming Yu3Zhenning Su4Xuetao Shi5Jianhua Zhou6Key Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou 510006, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou 510006, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou 510006, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou 510006, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou 510006, ChinaNational Engineering Research Centre for Tissue Restoration and Reconstruction, School of Material Science and Engineering, South China University of Technology, Guangzhou 510640, ChinaKey Laboratory of Sensing Technology and Biomedical Instruments of Guangdong Province, School of Biomedical Engineering, Sun Yat-Sen University, Guangzhou 510006, ChinaHigh-throughput screening is a potent technique to accelerate the discovery and development of new materials. By performing massive synthesis and characterization processes in parallel, it can rapidly discover materials with desired components, structures and functions. Among the various approaches for high-throughput screening, microfluidic platforms have attracted increasing attention. Compared with many current strategies that are generally based on robotic dispensers and automatic microplates, microfluidic platforms can significantly increase the throughput and reduce the consumption of reagents by several orders of magnitude. In this review, we first introduce current advances of the two types of microfluidic high-throughput platforms based on microarrays and microdroplets, respectively. Then the utilization of these platforms for screening different types of materials, including inorganic metals, metal alloys and organic polymers are described in detail. Finally, the challenges and opportunities in this promising field are critically discussed.https://www.mdpi.com/2079-4991/10/12/2514high-throughput platformsmaterials screeningmicroarraymicrofluidic dropletmicro/nano-structures |
spellingShingle | Peipei Zhou Jinxu He Lu Huang Ziming Yu Zhenning Su Xuetao Shi Jianhua Zhou Microfluidic High-Throughput Platforms for Discovery of Novel Materials Nanomaterials high-throughput platforms materials screening microarray microfluidic droplet micro/nano-structures |
title | Microfluidic High-Throughput Platforms for Discovery of Novel Materials |
title_full | Microfluidic High-Throughput Platforms for Discovery of Novel Materials |
title_fullStr | Microfluidic High-Throughput Platforms for Discovery of Novel Materials |
title_full_unstemmed | Microfluidic High-Throughput Platforms for Discovery of Novel Materials |
title_short | Microfluidic High-Throughput Platforms for Discovery of Novel Materials |
title_sort | microfluidic high throughput platforms for discovery of novel materials |
topic | high-throughput platforms materials screening microarray microfluidic droplet micro/nano-structures |
url | https://www.mdpi.com/2079-4991/10/12/2514 |
work_keys_str_mv | AT peipeizhou microfluidichighthroughputplatformsfordiscoveryofnovelmaterials AT jinxuhe microfluidichighthroughputplatformsfordiscoveryofnovelmaterials AT luhuang microfluidichighthroughputplatformsfordiscoveryofnovelmaterials AT zimingyu microfluidichighthroughputplatformsfordiscoveryofnovelmaterials AT zhenningsu microfluidichighthroughputplatformsfordiscoveryofnovelmaterials AT xuetaoshi microfluidichighthroughputplatformsfordiscoveryofnovelmaterials AT jianhuazhou microfluidichighthroughputplatformsfordiscoveryofnovelmaterials |