Locally relapsed and metastatic uterine leiomyoma: A case report
<p>Abstract</p> <p>Introduction</p> <p>Benign metastasising leiomyoma refers to a type of lesion characterised by leiomyomatous alterations without any indication of malignancy. It presents as either a singular nodule or multiple nodules of proliferating smooth muscle c...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2008-09-01
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| Series: | Journal of Medical Case Reports |
| Online Access: | http://www.jmedicalcasereports.com/content/2/1/308 |
| _version_ | 1818327746602860544 |
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| author | Londero Ambrogio P Perego Patrizia Mangioni Costantino Lellé Ralph J Londero Franco Marchesoni Diego |
| author_facet | Londero Ambrogio P Perego Patrizia Mangioni Costantino Lellé Ralph J Londero Franco Marchesoni Diego |
| author_sort | Londero Ambrogio P |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Introduction</p> <p>Benign metastasising leiomyoma refers to a type of lesion characterised by leiomyomatous alterations without any indication of malignancy. It presents as either a singular nodule or multiple nodules of proliferating smooth muscle cells and is generally found in the lungs of women who have undergone a hysterectomy. The purpose of this case report is to contribute to the knowledge of this rare disease by presenting evidence and experience of a patient case. In particular, this report seeks to investigate the therapeutic approaches in order to understand whether a standard of care can be prescribed and whether the use of prophylaxis therapy with progesterone as a follow-up to surgery serves as a reasonable treatment in certain cases diagnosed as benign metastasising leiomyoma.</p> <p>Case presentation</p> <p>We present the case of a 52-year-old Caucasian woman who developed a pelvic relapse and a pulmonary localisation of benign metastasising leiomyoma following a hysterectomy for myomatous uterus.</p> <p>Conclusion</p> <p>Our literature review revealed a single case of the use of chemoprophylaxis as treatment of a benign metastasising leiomyoma. The role of chemoprophylaxis in preventing future recurrences remains unclear. The use of progesterone as an adjuvant therapy for benign metastasising leiomyoma could simply be palliative, with associated psychological benefits, or it could be of therapeutic significance.</p> |
| first_indexed | 2024-12-13T12:21:10Z |
| format | Article |
| id | doaj.art-c34cc8da861944d6997935a944e924dd |
| institution | Directory Open Access Journal |
| issn | 1752-1947 |
| language | English |
| last_indexed | 2024-12-13T12:21:10Z |
| publishDate | 2008-09-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Medical Case Reports |
| spelling | doaj.art-c34cc8da861944d6997935a944e924dd2022-12-21T23:46:35ZengBMCJournal of Medical Case Reports1752-19472008-09-012130810.1186/1752-1947-2-308Locally relapsed and metastatic uterine leiomyoma: A case reportLondero Ambrogio PPerego PatriziaMangioni CostantinoLellé Ralph JLondero FrancoMarchesoni Diego<p>Abstract</p> <p>Introduction</p> <p>Benign metastasising leiomyoma refers to a type of lesion characterised by leiomyomatous alterations without any indication of malignancy. It presents as either a singular nodule or multiple nodules of proliferating smooth muscle cells and is generally found in the lungs of women who have undergone a hysterectomy. The purpose of this case report is to contribute to the knowledge of this rare disease by presenting evidence and experience of a patient case. In particular, this report seeks to investigate the therapeutic approaches in order to understand whether a standard of care can be prescribed and whether the use of prophylaxis therapy with progesterone as a follow-up to surgery serves as a reasonable treatment in certain cases diagnosed as benign metastasising leiomyoma.</p> <p>Case presentation</p> <p>We present the case of a 52-year-old Caucasian woman who developed a pelvic relapse and a pulmonary localisation of benign metastasising leiomyoma following a hysterectomy for myomatous uterus.</p> <p>Conclusion</p> <p>Our literature review revealed a single case of the use of chemoprophylaxis as treatment of a benign metastasising leiomyoma. The role of chemoprophylaxis in preventing future recurrences remains unclear. The use of progesterone as an adjuvant therapy for benign metastasising leiomyoma could simply be palliative, with associated psychological benefits, or it could be of therapeutic significance.</p>http://www.jmedicalcasereports.com/content/2/1/308 |
| spellingShingle | Londero Ambrogio P Perego Patrizia Mangioni Costantino Lellé Ralph J Londero Franco Marchesoni Diego Locally relapsed and metastatic uterine leiomyoma: A case report Journal of Medical Case Reports |
| title | Locally relapsed and metastatic uterine leiomyoma: A case report |
| title_full | Locally relapsed and metastatic uterine leiomyoma: A case report |
| title_fullStr | Locally relapsed and metastatic uterine leiomyoma: A case report |
| title_full_unstemmed | Locally relapsed and metastatic uterine leiomyoma: A case report |
| title_short | Locally relapsed and metastatic uterine leiomyoma: A case report |
| title_sort | locally relapsed and metastatic uterine leiomyoma a case report |
| url | http://www.jmedicalcasereports.com/content/2/1/308 |
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