Clip and wire localization of locally advanced malignant breast masses in patients undergoing neoadjuvant chemotherapy and breast conservation therapy
Abstract Background In locally advanced breast cancers, the use of preoperative systemic therapy has been shown to induce tumor response and to improve the local control rate after subsequent surgery and radiation therapy. The purpose of the study is to evaluate the accuracy of localization of breas...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2019-12-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43055-019-0066-z |
| _version_ | 1819060798187634688 |
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| author | Lamiaa Adel Salah El Din Shalaby Emad Salah el din Khallaf Mohamed Mahmoud Moussa |
| author_facet | Lamiaa Adel Salah El Din Shalaby Emad Salah el din Khallaf Mohamed Mahmoud Moussa |
| author_sort | Lamiaa Adel Salah El Din Shalaby |
| collection | DOAJ |
| description | Abstract Background In locally advanced breast cancers, the use of preoperative systemic therapy has been shown to induce tumor response and to improve the local control rate after subsequent surgery and radiation therapy. The purpose of the study is to evaluate the accuracy of localization of breast malignant masses in patients who received neoadjuvant chemotherapy and will undergo conservative breast surgery by using clip and wire marker. Results Clip placement was done in 20/20 cases (100%). There was no mammographic evidence of clip migration or complication related to the clip insertion. Wire localization of tumor bed marked by radiopaque clip 1-day preoperative was done in 18/20 patient (90%), the other 2 patients, the masses were clinically palpable (10%). Accurate localization by wire was positive in 18/18 cases. Clip and wire retrieval were positive in all cases. Conclusion Clip markers can be used for tumor localization in breast cancer patients undergoing neoadjuvant chemotherapy without migration. Clips are tolerated and safe for the patient, easily visualized on imaging, do not interfere with treatment response, and are cost-effective. Also, serves as a guide for post-neoadjuvant chemotherapy localization when the tumor is not palpable. |
| first_indexed | 2024-12-21T14:32:43Z |
| format | Article |
| id | doaj.art-c34dbd573f8d460887738668f49b1461 |
| institution | Directory Open Access Journal |
| issn | 2090-4762 |
| language | English |
| last_indexed | 2024-12-21T14:32:43Z |
| publishDate | 2019-12-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-c34dbd573f8d460887738668f49b14612022-12-21T19:00:27ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622019-12-015011910.1186/s43055-019-0066-zClip and wire localization of locally advanced malignant breast masses in patients undergoing neoadjuvant chemotherapy and breast conservation therapyLamiaa Adel Salah El Din Shalaby0Emad Salah el din Khallaf1Mohamed Mahmoud Moussa2Radiology Department (Women’s Imaging Unit), Faculty of Medicine, Kasr ElAiny Hospital, Cairo UniversityDepartment Faculty of Medicine, Kasr Al-Ainy Hospital, Cairo UniversityOncology Department, Faculty of Medicine, Kasr ElAiny Hospital, Cairo UniversityAbstract Background In locally advanced breast cancers, the use of preoperative systemic therapy has been shown to induce tumor response and to improve the local control rate after subsequent surgery and radiation therapy. The purpose of the study is to evaluate the accuracy of localization of breast malignant masses in patients who received neoadjuvant chemotherapy and will undergo conservative breast surgery by using clip and wire marker. Results Clip placement was done in 20/20 cases (100%). There was no mammographic evidence of clip migration or complication related to the clip insertion. Wire localization of tumor bed marked by radiopaque clip 1-day preoperative was done in 18/20 patient (90%), the other 2 patients, the masses were clinically palpable (10%). Accurate localization by wire was positive in 18/18 cases. Clip and wire retrieval were positive in all cases. Conclusion Clip markers can be used for tumor localization in breast cancer patients undergoing neoadjuvant chemotherapy without migration. Clips are tolerated and safe for the patient, easily visualized on imaging, do not interfere with treatment response, and are cost-effective. Also, serves as a guide for post-neoadjuvant chemotherapy localization when the tumor is not palpable.https://doi.org/10.1186/s43055-019-0066-zClipWireLocally advanced breast cancerNeoadjuvant chemotherapyConservative breast surgery |
| spellingShingle | Lamiaa Adel Salah El Din Shalaby Emad Salah el din Khallaf Mohamed Mahmoud Moussa Clip and wire localization of locally advanced malignant breast masses in patients undergoing neoadjuvant chemotherapy and breast conservation therapy The Egyptian Journal of Radiology and Nuclear Medicine Clip Wire Locally advanced breast cancer Neoadjuvant chemotherapy Conservative breast surgery |
| title | Clip and wire localization of locally advanced malignant breast masses in patients undergoing neoadjuvant chemotherapy and breast conservation therapy |
| title_full | Clip and wire localization of locally advanced malignant breast masses in patients undergoing neoadjuvant chemotherapy and breast conservation therapy |
| title_fullStr | Clip and wire localization of locally advanced malignant breast masses in patients undergoing neoadjuvant chemotherapy and breast conservation therapy |
| title_full_unstemmed | Clip and wire localization of locally advanced malignant breast masses in patients undergoing neoadjuvant chemotherapy and breast conservation therapy |
| title_short | Clip and wire localization of locally advanced malignant breast masses in patients undergoing neoadjuvant chemotherapy and breast conservation therapy |
| title_sort | clip and wire localization of locally advanced malignant breast masses in patients undergoing neoadjuvant chemotherapy and breast conservation therapy |
| topic | Clip Wire Locally advanced breast cancer Neoadjuvant chemotherapy Conservative breast surgery |
| url | https://doi.org/10.1186/s43055-019-0066-z |
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