Addressing a Pre-Clinical Pipeline Gap: Development of the Pediatric Acute Myeloid Leukemia Patient-Derived Xenograft Program at Texas Children’s Hospital at Baylor College of Medicine

Addressing a Pre-Clinical Pipeline Gap: Development of the Pediatric Acute Myeloid Leukemia Patient-Derived Xenograft Program at Texas Children’s Hospital at Baylor College of Medicine

The survival rate of pediatric acute myeloid leukemia (pAML) is currently around 60%. While survival has slowly increased over the past few decades, the development of novel agents likely to further improve survival for this heterogeneous patient population has been limited by gaps in the pAML pre-c...

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Bibliographic Details
Main Authors: Alexandra M. Stevens, Maci Terrell, Raushan Rashid, Kevin E. Fisher, Andrea N. Marcogliese, Amos Gaikwad, Pulivarthi Rao, Chelsea Vrana, Michael Krueger, Michael Loken, Andrew J. Menssen, Jacqueline A. Cook, Noah Keogh, Michelle Alozie, Hailey Oviedo, Alan K. Gonzalez, Tamilini Ilangovan, Julia Kim, Sohani Sandhu, Michele S. Redell
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Biomedicines
Subjects:
PDX development
Children’s Oncology Group (COG)
serial transplanting
BCM PDX portal
future development
NSGS
Online Access:https://www.mdpi.com/2227-9059/12/2/394

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https://www.mdpi.com/2227-9059/12/2/394

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