Potentiation of Schaffer-collateral CA1 synaptic transmission by eEF2K and p38 MAPK mediated mechanisms

The elongation factor 2 kinase (eEF2K), likewise known as CaMKIII, has been demonstrated to be involved in antidepressant responses of NMDA receptor antagonists. Even so, it remains open whether direct inhibition of eEF2K without altering up-flow or other signaling pathways affects hippocampal synap...

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Bibliographic Details
Main Authors: Weiguang Weng, Ying Chen, Man Wang, Yinghan Zhuang, Thomas Behnisch
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00247/full