Cell-attribute aware community detection improves differential abundance testing from single-cell RNA-Seq data

Cell-attribute aware community detection improves differential abundance testing from single-cell RNA-Seq data

Abstract Variations of cell-type proportions within tissues could be informative of biological aging and disease risk. Single-cell RNA-sequencing offers the opportunity to detect such differential abundance patterns, yet this task can be statistically challenging due to the noise in single-cell data...

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Bibliographic Details
Main Authors:	Alok K. Maity, Andrew E. Teschendorff
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-06-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-023-39017-z

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