Hexanucleotide motifs mediate recruitment of the RNA elimination machinery to silent meiotic genes

Hexanucleotide motifs mediate recruitment of the RNA elimination machinery to silent meiotic genes

The selective elimination system blocks the accumulation of meiosis-specific mRNAs during the mitotic cell cycle in fission yeast. These mRNAs harbour a region, the determinant of selective removal (DSR), which is recognized by a YTH-family RNA-binding protein, Mmi1. Mmi1 directs target transcripts...

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Bibliographic Details
Main Authors: Akira Yamashita, Yuichi Shichino, Hirotsugu Tanaka, Edwige Hiriart, Leila Touat-Todeschini, Aurélia Vavasseur, Da-Qiao Ding, Yasushi Hiraoka, André Verdel, Masayuki Yamamoto
Format: Article
Language:English
Published: The Royal Society 2012-01-01
Series:Open Biology
Subjects:
mrna degradation
rna-binding protein
exosome
meiosis
mmi1
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.120014

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