Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation

Atrial fibrillation (AF) is one of the most common tachyarrhythmias, contributing to both environmental and genetic factors, a clear understanding of which can be extremely important for determining management tactics and predicting the disease course. The article provides a brief overview of studie...

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Bibliographic Details
Main Authors: S. Yu. Nikulina, K. Yu. Shishkova, V. A. Shulman, A. A. Chernova, V. N. Maximov
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2021-08-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/4148
Description
Summary:Atrial fibrillation (AF) is one of the most common tachyarrhythmias, contributing to both environmental and genetic factors, a clear understanding of which can be extremely important for determining management tactics and predicting the disease course. The article provides a brief overview of studies on genetic predictors of AF, in particular, SNP markers found on chromosome 10. Establishing a relationship between the identified SNPs on chromosome 10 and functional genes, changes in the structure or regulation of which can affect the development of AF, opens the veil of understanding how these SNPs affect the pathogenesis of AF.
ISSN:1560-4071
2618-7620