Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation
Atrial fibrillation (AF) is one of the most common tachyarrhythmias, contributing to both environmental and genetic factors, a clear understanding of which can be extremely important for determining management tactics and predicting the disease course. The article provides a brief overview of studie...
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Format: | Article |
Language: | Russian |
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«FIRMA «SILICEA» LLC
2021-08-01
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Series: | Российский кардиологический журнал |
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Online Access: | https://russjcardiol.elpub.ru/jour/article/view/4148 |
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author | S. Yu. Nikulina K. Yu. Shishkova V. A. Shulman A. A. Chernova V. N. Maximov |
author_facet | S. Yu. Nikulina K. Yu. Shishkova V. A. Shulman A. A. Chernova V. N. Maximov |
author_sort | S. Yu. Nikulina |
collection | DOAJ |
description | Atrial fibrillation (AF) is one of the most common tachyarrhythmias, contributing to both environmental and genetic factors, a clear understanding of which can be extremely important for determining management tactics and predicting the disease course. The article provides a brief overview of studies on genetic predictors of AF, in particular, SNP markers found on chromosome 10. Establishing a relationship between the identified SNPs on chromosome 10 and functional genes, changes in the structure or regulation of which can affect the development of AF, opens the veil of understanding how these SNPs affect the pathogenesis of AF. |
first_indexed | 2024-04-09T20:44:54Z |
format | Article |
id | doaj.art-c359f941454244e995506d9dd87f393a |
institution | Directory Open Access Journal |
issn | 1560-4071 2618-7620 |
language | Russian |
last_indexed | 2025-03-14T09:26:25Z |
publishDate | 2021-08-01 |
publisher | «FIRMA «SILICEA» LLC |
record_format | Article |
series | Российский кардиологический журнал |
spelling | doaj.art-c359f941454244e995506d9dd87f393a2025-03-02T11:42:53Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202021-08-0126710.15829/1560-4071-2021-41483175Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillationS. Yu. Nikulina0K. Yu. Shishkova1V. A. Shulman2A. A. Chernova3V. N. Maximov4V.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityResearch Institute of Internal and Preventive MedicineAtrial fibrillation (AF) is one of the most common tachyarrhythmias, contributing to both environmental and genetic factors, a clear understanding of which can be extremely important for determining management tactics and predicting the disease course. The article provides a brief overview of studies on genetic predictors of AF, in particular, SNP markers found on chromosome 10. Establishing a relationship between the identified SNPs on chromosome 10 and functional genes, changes in the structure or regulation of which can affect the development of AF, opens the veil of understanding how these SNPs affect the pathogenesis of AF.https://russjcardiol.elpub.ru/jour/article/view/4148atrial fibrillationgenetic markerssnpchromosome 10<i>synpo2l</i><i>myoz1</i> |
spellingShingle | S. Yu. Nikulina K. Yu. Shishkova V. A. Shulman A. A. Chernova V. N. Maximov Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation Российский кардиологический журнал atrial fibrillation genetic markers snp chromosome 10 <i>synpo2l</i> <i>myoz1</i> |
title | Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation |
title_full | Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation |
title_fullStr | Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation |
title_full_unstemmed | Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation |
title_short | Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation |
title_sort | role of snp markers on chromosome 10 in the pathogenesis of atrial fibrillation |
topic | atrial fibrillation genetic markers snp chromosome 10 <i>synpo2l</i> <i>myoz1</i> |
url | https://russjcardiol.elpub.ru/jour/article/view/4148 |
work_keys_str_mv | AT syunikulina roleofsnpmarkersonchromosome10inthepathogenesisofatrialfibrillation AT kyushishkova roleofsnpmarkersonchromosome10inthepathogenesisofatrialfibrillation AT vashulman roleofsnpmarkersonchromosome10inthepathogenesisofatrialfibrillation AT aachernova roleofsnpmarkersonchromosome10inthepathogenesisofatrialfibrillation AT vnmaximov roleofsnpmarkersonchromosome10inthepathogenesisofatrialfibrillation |