Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation

Atrial fibrillation (AF) is one of the most common tachyarrhythmias, contributing to both environmental and genetic factors, a clear understanding of which can be extremely important for determining management tactics and predicting the disease course. The article provides a brief overview of studie...

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Main Authors: S. Yu. Nikulina, K. Yu. Shishkova, V. A. Shulman, A. A. Chernova, V. N. Maximov
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2021-08-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/4148
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author S. Yu. Nikulina
K. Yu. Shishkova
V. A. Shulman
A. A. Chernova
V. N. Maximov
author_facet S. Yu. Nikulina
K. Yu. Shishkova
V. A. Shulman
A. A. Chernova
V. N. Maximov
author_sort S. Yu. Nikulina
collection DOAJ
description Atrial fibrillation (AF) is one of the most common tachyarrhythmias, contributing to both environmental and genetic factors, a clear understanding of which can be extremely important for determining management tactics and predicting the disease course. The article provides a brief overview of studies on genetic predictors of AF, in particular, SNP markers found on chromosome 10. Establishing a relationship between the identified SNPs on chromosome 10 and functional genes, changes in the structure or regulation of which can affect the development of AF, opens the veil of understanding how these SNPs affect the pathogenesis of AF.
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spelling doaj.art-c359f941454244e995506d9dd87f393a2023-03-29T21:23:37Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202021-08-0126710.15829/1560-4071-2021-41483175Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillationS. Yu. Nikulina0K. Yu. Shishkova1V. A. Shulman2A. A. Chernova3V. N. Maximov4V.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityV.F. Voino-Yasenetsky Krasnoyarsk State Medical UniversityResearch Institute of Internal and Preventive MedicineAtrial fibrillation (AF) is one of the most common tachyarrhythmias, contributing to both environmental and genetic factors, a clear understanding of which can be extremely important for determining management tactics and predicting the disease course. The article provides a brief overview of studies on genetic predictors of AF, in particular, SNP markers found on chromosome 10. Establishing a relationship between the identified SNPs on chromosome 10 and functional genes, changes in the structure or regulation of which can affect the development of AF, opens the veil of understanding how these SNPs affect the pathogenesis of AF.https://russjcardiol.elpub.ru/jour/article/view/4148atrial fibrillationgenetic markerssnpchromosome 10<i>synpo2l</i><i>myoz1</i>
spellingShingle S. Yu. Nikulina
K. Yu. Shishkova
V. A. Shulman
A. A. Chernova
V. N. Maximov
Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation
Российский кардиологический журнал
atrial fibrillation
genetic markers
snp
chromosome 10
<i>synpo2l</i>
<i>myoz1</i>
title Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation
title_full Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation
title_fullStr Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation
title_full_unstemmed Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation
title_short Role of SNP markers on chromosome 10 in the pathogenesis of atrial fibrillation
title_sort role of snp markers on chromosome 10 in the pathogenesis of atrial fibrillation
topic atrial fibrillation
genetic markers
snp
chromosome 10
<i>synpo2l</i>
<i>myoz1</i>
url https://russjcardiol.elpub.ru/jour/article/view/4148
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AT kyushishkova roleofsnpmarkersonchromosome10inthepathogenesisofatrialfibrillation
AT vashulman roleofsnpmarkersonchromosome10inthepathogenesisofatrialfibrillation
AT aachernova roleofsnpmarkersonchromosome10inthepathogenesisofatrialfibrillation
AT vnmaximov roleofsnpmarkersonchromosome10inthepathogenesisofatrialfibrillation