Exploiting the endogenous yeast nuclear proteome to identify short linear motifs in vivo

Summary: Peptide-domain interactions mediated by short linear motifs (SLiMs) play crucial roles in cellular biology. The simplicity of SLiMs poses challenges in their computational identification. Existing high-throughput methods for discovering SLiMs lack cellular context as they are typically perf...

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Bibliographic Details
Main Authors: Tanner M. Tessier, Cason R. King, Joe S. Mymryk
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Cell Reports: Methods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667237523003089