A sphingolipid-dependent diffusion barrier confines ER stress to the yeast mother cell

In many cell types, lateral diffusion barriers compartmentalize the plasma membrane and, at least in budding yeast, the endoplasmic reticulum (ER). However, the molecular nature of these barriers, their mode of action and their cellular functions are unclear. Here, we show that misfolded proteins of...

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Bibliographic Details
Main Authors: Lori Clay, Fabrice Caudron, Annina Denoth-Lippuner, Barbara Boettcher, Stéphanie Buvelot Frei, Erik Lee Snapp, Yves Barral
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/01883

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