Zedoarondiol Inhibits Platelet-Derived Growth Factor-Induced Vascular Smooth Muscle Cells Proliferation via Regulating AMP-Activated Protein Kinase Signaling Pathway

Zedoarondiol Inhibits Platelet-Derived Growth Factor-Induced Vascular Smooth Muscle Cells Proliferation via Regulating AMP-Activated Protein Kinase Signaling Pathway

Background/Aims: Vascular smooth muscle cells (VSMCs) proliferation contributes significantly to atherosclerosis and in-stent restenosis. Platelet-derived growth factor-BB (PDGF-BB) plays a vital role in VSMCs proliferation. Zedoarondiol, a sesquiterpene lactone compound, has an anti-inflammatory ac...

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Bibliographic Details
Main Authors:	Huimin Mao, Tianqi Tao, Dandan Song, Mi Liu, Xiaoren Wang, Xiuhua Liu, Dazhuo Shi
Format:	Article
Language:	English
Published:	Cell Physiol Biochem Press GmbH & Co KG 2016-12-01
Series:	Cellular Physiology and Biochemistry
Subjects:	Zedoarondiol Vascular smooth muscle cell Proliferation AMP-activated protein kinase
Online Access:	http://www.karger.com/Article/FullText/453201

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