Clustered regularly interspaced short palindromic repeats screens in pediatric tumours: A review

Clustered regularly interspaced short palindromic repeats screens in pediatric tumours: A review

Abstract In recent years, the discovery and development of clustered regularly interspaced short palindromic repeats (CRISPR) technology has revolutionized and accelerated functional genetic screening in cancer research. In this review, we discuss different methods of executing CRISPR screens, with...

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Bibliographic Details
Main Authors: Madelaine G. vanMackelenbergh, Dennis S. Metselaar, Michaël H. Meel, Esther Hulleman
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Clinical and Translational Discovery
Subjects:
CRISPR
genetic screen
pediatric cancer
review
synthetic lethality
Online Access:https://doi.org/10.1002/ctd2.142

Internet

https://doi.org/10.1002/ctd2.142

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