Determination of EGFR endocytosis kinetic by auto-regulatory association of PLD1 with mu2.
BACKGROUND:Upon ligand binding, cell surface signaling receptors are internalized through a process tightly regulated by endocytic proteins and adaptor protein 2 (AP2) to orchestrate them. Although the molecular identities and roles of endocytic proteins are becoming clearer, it is still unclear wha...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-09-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC2739277?pdf=render |