Nano-Engineered Biomimetic Optical Sensors for Glucose Monitoring in Diabetes

Diabetes is a rapidly growing disease that can be monitored at an individual level by controlling the blood glucose level, hence minimizing the negative impact of the disease. Significant research efforts have been focused on the design of novel and improved technologies to overcome the limitations...

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Main Authors: Sajid Rauf, Muhammad Azhar Hayat Nawaz, Mihaela Badea, Jean Louis Marty, Akhtar Hayat
Format: Article
Language:English
Published: MDPI AG 2016-11-01
Series:Sensors
Subjects:
Online Access:http://www.mdpi.com/1424-8220/16/11/1931
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author Sajid Rauf
Muhammad Azhar Hayat Nawaz
Mihaela Badea
Jean Louis Marty
Akhtar Hayat
author_facet Sajid Rauf
Muhammad Azhar Hayat Nawaz
Mihaela Badea
Jean Louis Marty
Akhtar Hayat
author_sort Sajid Rauf
collection DOAJ
description Diabetes is a rapidly growing disease that can be monitored at an individual level by controlling the blood glucose level, hence minimizing the negative impact of the disease. Significant research efforts have been focused on the design of novel and improved technologies to overcome the limitations of existing glucose analysis methods. In this context, nanotechnology has enabled the diagnosis at the single cell and molecular level with the possibility of incorporation in advanced molecular diagnostic biochips. Recent years have witnessed the exploration and synthesis of various types of nanomaterials with enzyme-like properties, with their subsequent integration into the design of biomimetic optical sensors for glucose monitoring. This review paper will provide insights on the type, nature and synthesis of different biomimetic nanomaterials. Moreover, recent developments in the integration of these nanomaterials for optical glucose biosensing will be highlighted, with a final discussion on the challenges that must be addressed for successful implementation of these nano-devices in the clinical applications is presented.
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spelling doaj.art-c36f25f2085f489eb58f2a329fbd95462022-12-22T02:52:37ZengMDPI AGSensors1424-82202016-11-011611193110.3390/s16111931s16111931Nano-Engineered Biomimetic Optical Sensors for Glucose Monitoring in DiabetesSajid Rauf0Muhammad Azhar Hayat Nawaz1Mihaela Badea2Jean Louis Marty3Akhtar Hayat4Interdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS Institute of Information Technology, 54000 Lahore, PakistanInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS Institute of Information Technology, 54000 Lahore, PakistanFaculty of Medicine, Transilvania University of Brasov, 500019 Brasov, RomaniaBAE Laboratory, Universite de Perpignan Via Domitia, 66860 Perpignan, FranceInterdisciplinary Research Centre in Biomedical Materials (IRCBM), COMSATS Institute of Information Technology, 54000 Lahore, PakistanDiabetes is a rapidly growing disease that can be monitored at an individual level by controlling the blood glucose level, hence minimizing the negative impact of the disease. Significant research efforts have been focused on the design of novel and improved technologies to overcome the limitations of existing glucose analysis methods. In this context, nanotechnology has enabled the diagnosis at the single cell and molecular level with the possibility of incorporation in advanced molecular diagnostic biochips. Recent years have witnessed the exploration and synthesis of various types of nanomaterials with enzyme-like properties, with their subsequent integration into the design of biomimetic optical sensors for glucose monitoring. This review paper will provide insights on the type, nature and synthesis of different biomimetic nanomaterials. Moreover, recent developments in the integration of these nanomaterials for optical glucose biosensing will be highlighted, with a final discussion on the challenges that must be addressed for successful implementation of these nano-devices in the clinical applications is presented.http://www.mdpi.com/1424-8220/16/11/1931nanotechnologybiomimetic nanomaterialsoptical sensorsglucose monitoringdiabetes
spellingShingle Sajid Rauf
Muhammad Azhar Hayat Nawaz
Mihaela Badea
Jean Louis Marty
Akhtar Hayat
Nano-Engineered Biomimetic Optical Sensors for Glucose Monitoring in Diabetes
Sensors
nanotechnology
biomimetic nanomaterials
optical sensors
glucose monitoring
diabetes
title Nano-Engineered Biomimetic Optical Sensors for Glucose Monitoring in Diabetes
title_full Nano-Engineered Biomimetic Optical Sensors for Glucose Monitoring in Diabetes
title_fullStr Nano-Engineered Biomimetic Optical Sensors for Glucose Monitoring in Diabetes
title_full_unstemmed Nano-Engineered Biomimetic Optical Sensors for Glucose Monitoring in Diabetes
title_short Nano-Engineered Biomimetic Optical Sensors for Glucose Monitoring in Diabetes
title_sort nano engineered biomimetic optical sensors for glucose monitoring in diabetes
topic nanotechnology
biomimetic nanomaterials
optical sensors
glucose monitoring
diabetes
url http://www.mdpi.com/1424-8220/16/11/1931
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AT muhammadazharhayatnawaz nanoengineeredbiomimeticopticalsensorsforglucosemonitoringindiabetes
AT mihaelabadea nanoengineeredbiomimeticopticalsensorsforglucosemonitoringindiabetes
AT jeanlouismarty nanoengineeredbiomimeticopticalsensorsforglucosemonitoringindiabetes
AT akhtarhayat nanoengineeredbiomimeticopticalsensorsforglucosemonitoringindiabetes