Validation of computational fluid dynamics of shake flask experiments at moderate viscosity by liquid distributions and volumetric power inputs
Abstract Computational fluid dynamics (CFD) has recently become a pivotal tool in the design and scale-up of bioprocesses. While CFD has been extensively utilized for stirred tank reactors (STRs), there exists a relatively limited body of literature focusing on CFD applications for shake flasks, alm...
Main Authors: | Carl Dinter, Andreas Gumprecht, Matthias Alexander Menze, Amizon Azizan, Paul-Joachim Niehoff, Sven Hansen, Jochen Büchs |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-02-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-53980-7 |
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