The Reliability of Histamine Pharmacodynamic Response Phenotype Classification in Children With Allergic Disease

The Reliability of Histamine Pharmacodynamic Response Phenotype Classification in Children With Allergic Disease

We have identified distinct histamine pharmacodynamic response phenotypes in children with allergic disease utilizing histamine iontophoresis with laser Doppler (HILD). These response phenotypes may be relevant in guiding therapeutic decision making for agents targeting the allergic response pathway...

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Bibliographic Details
Main Authors: Shaun S. Kumar, Xiaoxi Liu, Catherine M. Sherwin, Bridgette L. Jones
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Pharmacology
Subjects:
histamine
children
pharmacodynamics
allergy
phenotype
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00227/full

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