Chromogenic Mechanisms of Colorimetric Sensors Based on Gold Nanoparticles
The colorimetric signal readout method is widely used in visualized analyses for its advantages, including visualization of test results, simple and fast operations, low detection cost and fast response time. Gold nanoparticles (Au NPs), which not only exhibit enzyme-like activity but also have the...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-08-01
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| Series: | Biosensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6374/13/8/801 |
| _version_ | 1797585341955178496 |
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| author | Yanyun Cui Jun Zhao Huidan Li |
| author_facet | Yanyun Cui Jun Zhao Huidan Li |
| author_sort | Yanyun Cui |
| collection | DOAJ |
| description | The colorimetric signal readout method is widely used in visualized analyses for its advantages, including visualization of test results, simple and fast operations, low detection cost and fast response time. Gold nanoparticles (Au NPs), which not only exhibit enzyme-like activity but also have the advantages of tunable localized surface plasmon resonance (LSPR), high stability, good biocompatibility and easily modified properties, provide excellent platforms for the construction of colorimetric sensors. They are widely used in environmental monitoring, biomedicine, the food industry and other fields. This review focuses on the chromogenic mechanisms of colorimetric sensors based on Au NPs adopting two different sensing strategies and summarizes significant advances in Au NP-based colorimetric sensing with enzyme-like activity and tunable LSPR characteristics. In addition, the sensing strategies based on the LSPR properties of Au NPs are classified into four modulation methods: aggregation, surface modification, deposition and etching, and the current status of visual detection of various analytes is discussed. Finally, the review further discusses the limitations of current Au NP-based detection strategies and the promising prospects of Au NPs as colorimetric sensors, guiding the design of novel colorimetric sensors. |
| first_indexed | 2024-03-11T00:05:44Z |
| format | Article |
| id | doaj.art-c37a140137dd446895bd2036ff5804aa |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-11T00:05:44Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-c37a140137dd446895bd2036ff5804aa2023-11-19T00:25:26ZengMDPI AGBiosensors2079-63742023-08-0113880110.3390/bios13080801Chromogenic Mechanisms of Colorimetric Sensors Based on Gold NanoparticlesYanyun Cui0Jun Zhao1Huidan Li2College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, ChinaCollege of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, ChinaCollege of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, ChinaThe colorimetric signal readout method is widely used in visualized analyses for its advantages, including visualization of test results, simple and fast operations, low detection cost and fast response time. Gold nanoparticles (Au NPs), which not only exhibit enzyme-like activity but also have the advantages of tunable localized surface plasmon resonance (LSPR), high stability, good biocompatibility and easily modified properties, provide excellent platforms for the construction of colorimetric sensors. They are widely used in environmental monitoring, biomedicine, the food industry and other fields. This review focuses on the chromogenic mechanisms of colorimetric sensors based on Au NPs adopting two different sensing strategies and summarizes significant advances in Au NP-based colorimetric sensing with enzyme-like activity and tunable LSPR characteristics. In addition, the sensing strategies based on the LSPR properties of Au NPs are classified into four modulation methods: aggregation, surface modification, deposition and etching, and the current status of visual detection of various analytes is discussed. Finally, the review further discusses the limitations of current Au NP-based detection strategies and the promising prospects of Au NPs as colorimetric sensors, guiding the design of novel colorimetric sensors.https://www.mdpi.com/2079-6374/13/8/801colorimetric sensinggold nanoparticlesenzyme-like activityaggregationsurface modificationdeposition |
| spellingShingle | Yanyun Cui Jun Zhao Huidan Li Chromogenic Mechanisms of Colorimetric Sensors Based on Gold Nanoparticles Biosensors colorimetric sensing gold nanoparticles enzyme-like activity aggregation surface modification deposition |
| title | Chromogenic Mechanisms of Colorimetric Sensors Based on Gold Nanoparticles |
| title_full | Chromogenic Mechanisms of Colorimetric Sensors Based on Gold Nanoparticles |
| title_fullStr | Chromogenic Mechanisms of Colorimetric Sensors Based on Gold Nanoparticles |
| title_full_unstemmed | Chromogenic Mechanisms of Colorimetric Sensors Based on Gold Nanoparticles |
| title_short | Chromogenic Mechanisms of Colorimetric Sensors Based on Gold Nanoparticles |
| title_sort | chromogenic mechanisms of colorimetric sensors based on gold nanoparticles |
| topic | colorimetric sensing gold nanoparticles enzyme-like activity aggregation surface modification deposition |
| url | https://www.mdpi.com/2079-6374/13/8/801 |
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