The neural mechanisms underlying the decision to rest in the presence of fatigue: a magnetoencephalography study.
Adequate rest is essential to avoid fatigue and disruption of homeostasis. However, the neural mechanisms underlying the decision to rest are not well understood. In the present study, we aimed to clarify the neural mechanisms of this decision-making process using magnetoencephalography. Fifteen hea...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC4193824?pdf=render |
| _version_ | 1828231635076644864 |
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| author | Akira Ishii Masaaki Tanaka Yasuyoshi Watanabe |
| author_facet | Akira Ishii Masaaki Tanaka Yasuyoshi Watanabe |
| author_sort | Akira Ishii |
| collection | DOAJ |
| description | Adequate rest is essential to avoid fatigue and disruption of homeostasis. However, the neural mechanisms underlying the decision to rest are not well understood. In the present study, we aimed to clarify the neural mechanisms of this decision-making process using magnetoencephalography. Fifteen healthy volunteers participated in decision and control experiments performed in a cross-over fashion. In the decision experiment, participants performed 1,200 reverse Stroop test trials and were intermittently asked to decide whether they wanted to take a rest or continue. In the control experiments, participants performed 1,200 reverse Stroop test trials and were instructed to press a response button intermittently without making any decision. Changes in oscillatory brain activity were assessed using a narrow-band adaptive spatial filtering method. The levels of decrease in theta (4-8 Hz) band power in left Brodmann's area (BA) 31, alpha (8-13 Hz) band power in left BA 10 and BA 9, and beta (13-25 Hz) band power in right BA 46 and left BA 10 were greater in trials when the participant opted to rest (rest trials) than those in control trials. The decrease in theta band power in BA 31 in the rest trials was positively correlated with the subjective level of fatigue after the decision experiment. These results demonstrated that the dorsolateral prefrontal cortex, frontal pole, and posterior cingulate cortex play a role in the decision to rest in the presence of fatigue. These findings may help clarify the neural mechanisms underlying fatigue and fatigue-related problems. |
| first_indexed | 2024-04-12T19:08:25Z |
| format | Article |
| id | doaj.art-c37c13cc40cd4d0dbec1f9aad5a94edb |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-12T19:08:25Z |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-c37c13cc40cd4d0dbec1f9aad5a94edb2022-12-22T03:19:58ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-01910e10974010.1371/journal.pone.0109740The neural mechanisms underlying the decision to rest in the presence of fatigue: a magnetoencephalography study.Akira IshiiMasaaki TanakaYasuyoshi WatanabeAdequate rest is essential to avoid fatigue and disruption of homeostasis. However, the neural mechanisms underlying the decision to rest are not well understood. In the present study, we aimed to clarify the neural mechanisms of this decision-making process using magnetoencephalography. Fifteen healthy volunteers participated in decision and control experiments performed in a cross-over fashion. In the decision experiment, participants performed 1,200 reverse Stroop test trials and were intermittently asked to decide whether they wanted to take a rest or continue. In the control experiments, participants performed 1,200 reverse Stroop test trials and were instructed to press a response button intermittently without making any decision. Changes in oscillatory brain activity were assessed using a narrow-band adaptive spatial filtering method. The levels of decrease in theta (4-8 Hz) band power in left Brodmann's area (BA) 31, alpha (8-13 Hz) band power in left BA 10 and BA 9, and beta (13-25 Hz) band power in right BA 46 and left BA 10 were greater in trials when the participant opted to rest (rest trials) than those in control trials. The decrease in theta band power in BA 31 in the rest trials was positively correlated with the subjective level of fatigue after the decision experiment. These results demonstrated that the dorsolateral prefrontal cortex, frontal pole, and posterior cingulate cortex play a role in the decision to rest in the presence of fatigue. These findings may help clarify the neural mechanisms underlying fatigue and fatigue-related problems.http://europepmc.org/articles/PMC4193824?pdf=render |
| spellingShingle | Akira Ishii Masaaki Tanaka Yasuyoshi Watanabe The neural mechanisms underlying the decision to rest in the presence of fatigue: a magnetoencephalography study. PLoS ONE |
| title | The neural mechanisms underlying the decision to rest in the presence of fatigue: a magnetoencephalography study. |
| title_full | The neural mechanisms underlying the decision to rest in the presence of fatigue: a magnetoencephalography study. |
| title_fullStr | The neural mechanisms underlying the decision to rest in the presence of fatigue: a magnetoencephalography study. |
| title_full_unstemmed | The neural mechanisms underlying the decision to rest in the presence of fatigue: a magnetoencephalography study. |
| title_short | The neural mechanisms underlying the decision to rest in the presence of fatigue: a magnetoencephalography study. |
| title_sort | neural mechanisms underlying the decision to rest in the presence of fatigue a magnetoencephalography study |
| url | http://europepmc.org/articles/PMC4193824?pdf=render |
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