Actions of Thyroid Hormone Analogues on Chemokines

The extracellular domain of plasma membrane integrin αvβ3 contains a receptor for thyroid hormone (L-thyroxine, T4; 3,5,3′-triiodo-L-thyronine, T3); this receptor also binds tetraiodothyroacetic acid (tetrac), a derivative of T4. Tetrac inhibits the binding of T4 and T3 to the integrin. Fractalkine...

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Bibliografiske detaljer
Main Authors: Paul J. Davis, Gennadi V. Glinsky, Hung-Yun Lin, Shaker A. Mousa
Format: Article
Sprog:English
Udgivet: Hindawi Limited 2016-01-01
Serier:Journal of Immunology Research
Online adgang:http://dx.doi.org/10.1155/2016/3147671