Diagnostics and treatment of chronic kidney disease in modern clinical guidelines: what do practitioners need to know?

Chronic kidney disease (CKD), widely prevalent in real-world clinical practice settings, is associated with an increased risk of cardiovascular and renal complications. Modern clinical guidelines on the management of CKD patients provide recommendations on the early diagnostics of renal functional a...

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Main Authors: V. V. Skibitskyi, A. V. Fendrikova
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2013-10-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/423
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author V. V. Skibitskyi
A. V. Fendrikova
author_facet V. V. Skibitskyi
A. V. Fendrikova
author_sort V. V. Skibitskyi
collection DOAJ
description Chronic kidney disease (CKD), widely prevalent in real-world clinical practice settings, is associated with an increased risk of cardiovascular and renal complications. Modern clinical guidelines on the management of CKD patients provide recommendations on the early diagnostics of renal functional and structural pathology, as well as on the adequate treatment which prevents or postpones the progression of these pathological changes. Currently, the assessment of glomerular filtration rate and albuminuria severity is considered obligatory in the CKD diagnostics. These criteria are reflected in the CKD classification, presented in the modern clinical guidelines. The presence of CKD requires the administration of effective treatment, including renin-angiotensin-aldosterone system (RAAS) blockers. At the same time, most CKD patients also require antihypertensive combination therapy, which includes RAAS blockers, diuretics, and/or calcium antagonists. The choice of antihypertensive agents is defined by the specific clinical situation. One of the effective calcium antagonists with proven nephroprotective activity is lercanidipine. The treatment of CKD patients should also include adequate glycemia control and lipid-lowering agents.
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spelling doaj.art-c37de6536d6743d193ab1af67af478f02023-03-29T21:23:20Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202013-10-0105667210.15829/1560-4071-2013-5-66-72423Diagnostics and treatment of chronic kidney disease in modern clinical guidelines: what do practitioners need to know?V. V. Skibitskyi0A. V. Fendrikova1Kuban State Medical University, Krasnodar, RussiaKuban State Medical University, Krasnodar, RussiaChronic kidney disease (CKD), widely prevalent in real-world clinical practice settings, is associated with an increased risk of cardiovascular and renal complications. Modern clinical guidelines on the management of CKD patients provide recommendations on the early diagnostics of renal functional and structural pathology, as well as on the adequate treatment which prevents or postpones the progression of these pathological changes. Currently, the assessment of glomerular filtration rate and albuminuria severity is considered obligatory in the CKD diagnostics. These criteria are reflected in the CKD classification, presented in the modern clinical guidelines. The presence of CKD requires the administration of effective treatment, including renin-angiotensin-aldosterone system (RAAS) blockers. At the same time, most CKD patients also require antihypertensive combination therapy, which includes RAAS blockers, diuretics, and/or calcium antagonists. The choice of antihypertensive agents is defined by the specific clinical situation. One of the effective calcium antagonists with proven nephroprotective activity is lercanidipine. The treatment of CKD patients should also include adequate glycemia control and lipid-lowering agents.https://russjcardiol.elpub.ru/jour/article/view/423chronic kidney diseaserenal functionalbuminuria
spellingShingle V. V. Skibitskyi
A. V. Fendrikova
Diagnostics and treatment of chronic kidney disease in modern clinical guidelines: what do practitioners need to know?
Российский кардиологический журнал
chronic kidney disease
renal function
albuminuria
title Diagnostics and treatment of chronic kidney disease in modern clinical guidelines: what do practitioners need to know?
title_full Diagnostics and treatment of chronic kidney disease in modern clinical guidelines: what do practitioners need to know?
title_fullStr Diagnostics and treatment of chronic kidney disease in modern clinical guidelines: what do practitioners need to know?
title_full_unstemmed Diagnostics and treatment of chronic kidney disease in modern clinical guidelines: what do practitioners need to know?
title_short Diagnostics and treatment of chronic kidney disease in modern clinical guidelines: what do practitioners need to know?
title_sort diagnostics and treatment of chronic kidney disease in modern clinical guidelines what do practitioners need to know
topic chronic kidney disease
renal function
albuminuria
url https://russjcardiol.elpub.ru/jour/article/view/423
work_keys_str_mv AT vvskibitskyi diagnosticsandtreatmentofchronickidneydiseaseinmodernclinicalguidelineswhatdopractitionersneedtoknow
AT avfendrikova diagnosticsandtreatmentofchronickidneydiseaseinmodernclinicalguidelineswhatdopractitionersneedtoknow