Comparison of Optimization Strategies for Musculoskeletal Modeling of the Wrist for Therapy Planning in Case of Total Wrist Arthroplasty

The human wrist joint is an elegant mechanism. The wrist allows the positioning and orienting of the hand to the forearm. The computational modeling of the human hand, especially of the wrist joint, can reveal important information about biomechanical mechanisms and provide the basis for its dysfunc...

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Main Authors: Jörg Eschweiler, Maximilian Praster, Valentin Quack, Jianzhang Li, Björn Rath, Frank Hildebrand, Filippo Migliorini
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/4/527
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author Jörg Eschweiler
Maximilian Praster
Valentin Quack
Jianzhang Li
Björn Rath
Frank Hildebrand
Filippo Migliorini
author_facet Jörg Eschweiler
Maximilian Praster
Valentin Quack
Jianzhang Li
Björn Rath
Frank Hildebrand
Filippo Migliorini
author_sort Jörg Eschweiler
collection DOAJ
description The human wrist joint is an elegant mechanism. The wrist allows the positioning and orienting of the hand to the forearm. The computational modeling of the human hand, especially of the wrist joint, can reveal important information about biomechanical mechanisms and provide the basis for its dysfunction and pathologies. For instance, this could be used for therapy planning in total wrist arthroplasty (TWA). In this study, different optimization methods and sensitivity analyses of anatomical parameters for musculoskeletal modeling were presented. Optimization includes finding the best available value of an objective function, including a variety of different types of objective functions. In the simplest case, optimization consists of maximizing or minimizing a function by systematically choosing input values from within an allowed set and computing the value of the function. Optimization techniques are used in many facets, such as the model building of joints or joint systems such as the wrist. The purpose of this study is to show the variability and influence of the included information for modeling, investigating the biomechanical function and load situation of the joint in representative scenarios. These possibilities to take them into account by an optimization and seem essential for the application of computational modeling to joint pathologies.
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spelling doaj.art-c37f22a4c5b7424aa4188344613fd2f02023-12-03T13:37:05ZengMDPI AGLife2075-17292022-04-0112452710.3390/life12040527Comparison of Optimization Strategies for Musculoskeletal Modeling of the Wrist for Therapy Planning in Case of Total Wrist ArthroplastyJörg Eschweiler0Maximilian Praster1Valentin Quack2Jianzhang Li3Björn Rath4Frank Hildebrand5Filippo Migliorini6Department of Orthopaedics, Trauma and Reconstructive Surgery, RWTH Aachen University Hospital, 52074 Aachen, GermanyDepartment of Orthopaedics, Trauma and Reconstructive Surgery, RWTH Aachen University Hospital, 52074 Aachen, GermanyDepartment of Orthopaedics, Trauma and Reconstructive Surgery, RWTH Aachen University Hospital, 52074 Aachen, GermanyDepartment of Orthopaedics, Trauma and Reconstructive Surgery, RWTH Aachen University Hospital, 52074 Aachen, GermanyDepartment of Orthopaedic Surgery, Klinikum Wels-Grieskirchen, 4600 Wels, AustriaDepartment of Orthopaedics, Trauma and Reconstructive Surgery, RWTH Aachen University Hospital, 52074 Aachen, GermanyDepartment of Orthopaedics, Trauma and Reconstructive Surgery, RWTH Aachen University Hospital, 52074 Aachen, GermanyThe human wrist joint is an elegant mechanism. The wrist allows the positioning and orienting of the hand to the forearm. The computational modeling of the human hand, especially of the wrist joint, can reveal important information about biomechanical mechanisms and provide the basis for its dysfunction and pathologies. For instance, this could be used for therapy planning in total wrist arthroplasty (TWA). In this study, different optimization methods and sensitivity analyses of anatomical parameters for musculoskeletal modeling were presented. Optimization includes finding the best available value of an objective function, including a variety of different types of objective functions. In the simplest case, optimization consists of maximizing or minimizing a function by systematically choosing input values from within an allowed set and computing the value of the function. Optimization techniques are used in many facets, such as the model building of joints or joint systems such as the wrist. The purpose of this study is to show the variability and influence of the included information for modeling, investigating the biomechanical function and load situation of the joint in representative scenarios. These possibilities to take them into account by an optimization and seem essential for the application of computational modeling to joint pathologies.https://www.mdpi.com/2075-1729/12/4/527modelingtotal wrist arthroplastybiomechanicsTWA
spellingShingle Jörg Eschweiler
Maximilian Praster
Valentin Quack
Jianzhang Li
Björn Rath
Frank Hildebrand
Filippo Migliorini
Comparison of Optimization Strategies for Musculoskeletal Modeling of the Wrist for Therapy Planning in Case of Total Wrist Arthroplasty
Life
modeling
total wrist arthroplasty
biomechanics
TWA
title Comparison of Optimization Strategies for Musculoskeletal Modeling of the Wrist for Therapy Planning in Case of Total Wrist Arthroplasty
title_full Comparison of Optimization Strategies for Musculoskeletal Modeling of the Wrist for Therapy Planning in Case of Total Wrist Arthroplasty
title_fullStr Comparison of Optimization Strategies for Musculoskeletal Modeling of the Wrist for Therapy Planning in Case of Total Wrist Arthroplasty
title_full_unstemmed Comparison of Optimization Strategies for Musculoskeletal Modeling of the Wrist for Therapy Planning in Case of Total Wrist Arthroplasty
title_short Comparison of Optimization Strategies for Musculoskeletal Modeling of the Wrist for Therapy Planning in Case of Total Wrist Arthroplasty
title_sort comparison of optimization strategies for musculoskeletal modeling of the wrist for therapy planning in case of total wrist arthroplasty
topic modeling
total wrist arthroplasty
biomechanics
TWA
url https://www.mdpi.com/2075-1729/12/4/527
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