Trim33 masks a non-transcriptional function of E2f4 in replication fork progression

Trim33 masks a non-transcriptional function of E2f4 in replication fork progression

Abstract Replicative stress promotes genomic instability and tumorigenesis but also presents an effective therapeutic endpoint, rationalizing detailed analysis of pathways that control DNA replication. We show here that the transcription factor E2f4 recruits the DNA helicase Recql to facilitate prog...

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Bibliographic Details
Main Authors:	Vanessa Rousseau, Elias Einig, Chao Jin, Julia Horn, Mathias Riebold, Tanja Poth, Mohamed-Ali Jarboui, Michael Flentje, Nikita Popov
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-08-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-023-40847-0

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