Reinvestigating the Neural Bases Involved in Speech Production of Stutterers: An ALE Meta-Analysis
Background: Stuttering is characterized by dysfluency and difficulty in speech production. Previous research has found abnormalities in the neural function of various brain areas during speech production tasks. However, the cognitive neural mechanism of stuttering has still not been fully determined...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/12/8/1030 |
| _version_ | 1797439166241308672 |
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| author | Ning Zhang Yulong Yin Yuchen Jiang Chenxu Huang |
| author_facet | Ning Zhang Yulong Yin Yuchen Jiang Chenxu Huang |
| author_sort | Ning Zhang |
| collection | DOAJ |
| description | Background: Stuttering is characterized by dysfluency and difficulty in speech production. Previous research has found abnormalities in the neural function of various brain areas during speech production tasks. However, the cognitive neural mechanism of stuttering has still not been fully determined. Method: Activation likelihood estimation analysis was performed to provide neural imaging evidence on neural bases by reanalyzing published studies. Results: Our analysis revealed overactivation in the bilateral posterior superior temporal gyrus, inferior frontal gyrus, medial frontal gyrus, precentral gyrus, postcentral gyrus, basal ganglia, and cerebellum, and deactivation in the anterior superior temporal gyrus and middle temporal gyrus among the stutterers. The overactivated regions might indicate a greater demand in feedforward planning in speech production, while the deactivated regions might indicate dysfunction in the auditory feedback system among stutterers. Conclusions: Our findings provide updated and direct evidence on the multi-level impairment (feedforward and feedback systems) of stutterers during speech production and show that the corresponding neural bases were differentiated. |
| first_indexed | 2024-03-09T11:48:47Z |
| format | Article |
| id | doaj.art-c381ac2661844dc99ea9efb385a054f1 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-09T11:48:47Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-c381ac2661844dc99ea9efb385a054f12023-11-30T23:18:05ZengMDPI AGBrain Sciences2076-34252022-08-01128103010.3390/brainsci12081030Reinvestigating the Neural Bases Involved in Speech Production of Stutterers: An ALE Meta-AnalysisNing Zhang0Yulong Yin1Yuchen Jiang2Chenxu Huang3CAS Key Laboratory of Behavioral Science, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, ChinaSchool of Psychology, Northwest Normal University, Lanzhou 730070, ChinaDepartment of Psychology, Renmin University of China, Beijing 100086, ChinaSchool of Arts, Renmin University of China, Beijing 100086, ChinaBackground: Stuttering is characterized by dysfluency and difficulty in speech production. Previous research has found abnormalities in the neural function of various brain areas during speech production tasks. However, the cognitive neural mechanism of stuttering has still not been fully determined. Method: Activation likelihood estimation analysis was performed to provide neural imaging evidence on neural bases by reanalyzing published studies. Results: Our analysis revealed overactivation in the bilateral posterior superior temporal gyrus, inferior frontal gyrus, medial frontal gyrus, precentral gyrus, postcentral gyrus, basal ganglia, and cerebellum, and deactivation in the anterior superior temporal gyrus and middle temporal gyrus among the stutterers. The overactivated regions might indicate a greater demand in feedforward planning in speech production, while the deactivated regions might indicate dysfunction in the auditory feedback system among stutterers. Conclusions: Our findings provide updated and direct evidence on the multi-level impairment (feedforward and feedback systems) of stutterers during speech production and show that the corresponding neural bases were differentiated.https://www.mdpi.com/2076-3425/12/8/1030stutteringneural basesmeta-analysisactivation likelihood estimation |
| spellingShingle | Ning Zhang Yulong Yin Yuchen Jiang Chenxu Huang Reinvestigating the Neural Bases Involved in Speech Production of Stutterers: An ALE Meta-Analysis Brain Sciences stuttering neural bases meta-analysis activation likelihood estimation |
| title | Reinvestigating the Neural Bases Involved in Speech Production of Stutterers: An ALE Meta-Analysis |
| title_full | Reinvestigating the Neural Bases Involved in Speech Production of Stutterers: An ALE Meta-Analysis |
| title_fullStr | Reinvestigating the Neural Bases Involved in Speech Production of Stutterers: An ALE Meta-Analysis |
| title_full_unstemmed | Reinvestigating the Neural Bases Involved in Speech Production of Stutterers: An ALE Meta-Analysis |
| title_short | Reinvestigating the Neural Bases Involved in Speech Production of Stutterers: An ALE Meta-Analysis |
| title_sort | reinvestigating the neural bases involved in speech production of stutterers an ale meta analysis |
| topic | stuttering neural bases meta-analysis activation likelihood estimation |
| url | https://www.mdpi.com/2076-3425/12/8/1030 |
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