Current natural bioactive materials in bone and tooth regeneration in dentistry: a comprehensive overview
Tissue regeneration is a vital phenomenon in the skeletal system of human beings during their life span. The structure of bony architecture and teeth are highly dependent to this ongoing procedure to maintain their functional form. Regarding the fundamental function of our skeletal system, all the i...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-07-01
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| Series: | Journal of Materials Research and Technology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2238785421005299 |
| _version_ | 1819071913594454016 |
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| author | Ehsan Tafazoli Moghadam Mohsen Yazdanian Mostafa Alam Hamid Tebyanian Ali Tafazoli Elahe Tahmasebi Reza Ranjbar Alireza Yazdanian Alexander Seifalian |
| author_facet | Ehsan Tafazoli Moghadam Mohsen Yazdanian Mostafa Alam Hamid Tebyanian Ali Tafazoli Elahe Tahmasebi Reza Ranjbar Alireza Yazdanian Alexander Seifalian |
| author_sort | Ehsan Tafazoli Moghadam |
| collection | DOAJ |
| description | Tissue regeneration is a vital phenomenon in the skeletal system of human beings during their life span. The structure of bony architecture and teeth are highly dependent to this ongoing procedure to maintain their functional form. Regarding the fundamental function of our skeletal system, all the involved components are at constant risk for injuries and deformations throughout the life. Therefore, in modern medicine, promotion of bone and tooth regeneration has become a critical counter measure to correct these acquired defects. There are numerous ways to address the bone and tooth related erosive pathologies but utilization of natural compounds has gained immense popularity in recent years. These materials provide a broad spectrum of therapeutic agents with a variety of biological characteristics. In this review, a comprehensive exploration has been implemented to extract and categorize the relevant scientific evidence on this issue, based on the source of natural candidates and the potential clinical indications. Database searching presented a considerable data pool with more than 300 references in this field. According to the results, all the proposed items can be categorized in two major groups including scaffolding and osteogenesis (or dentinogenesis) induction. The clinical applicability of a number of them is properly demonstrated in clinical trials but for the rest, more examinations are required to reach a conclusive decision. |
| first_indexed | 2024-12-21T17:29:23Z |
| format | Article |
| id | doaj.art-c38ad6305d9c45f7a5f8f61845896690 |
| institution | Directory Open Access Journal |
| issn | 2238-7854 |
| language | English |
| last_indexed | 2024-12-21T17:29:23Z |
| publishDate | 2021-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Materials Research and Technology |
| spelling | doaj.art-c38ad6305d9c45f7a5f8f618458966902022-12-21T18:55:58ZengElsevierJournal of Materials Research and Technology2238-78542021-07-011320782114Current natural bioactive materials in bone and tooth regeneration in dentistry: a comprehensive overviewEhsan Tafazoli Moghadam0Mohsen Yazdanian1Mostafa Alam2Hamid Tebyanian3Ali Tafazoli4Elahe Tahmasebi5Reza Ranjbar6Alireza Yazdanian7Alexander Seifalian8Research Center for Prevention of Oral and Dental Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran; School of Dentistry, Baqiyatallah University of Medical Sciences, Tehran, IranResearch Center for Prevention of Oral and Dental Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran; Corresponding author.Department of Oral and Maxillofacial Surgery, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, IranResearch Center for Prevention of Oral and Dental Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran; School of Dentistry, Baqiyatallah University of Medical Sciences, Tehran, Iran; Corresponding author.Clinical Pharmacy Department, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, IranResearch Center for Prevention of Oral and Dental Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran; School of Dentistry, Baqiyatallah University of Medical Sciences, Tehran, IranResearch Center for Prevention of Oral and Dental Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran; School of Dentistry, Baqiyatallah University of Medical Sciences, Tehran, IranDepartment of Veterinary, Science and Research Branch, Islamic Azad University, Tehran, IranNanotechnology and Regenerative Medicine Commercialization Centre (NanoRegMed Ltd), The London Bioscience Innovation Centre, London, United KingdomTissue regeneration is a vital phenomenon in the skeletal system of human beings during their life span. The structure of bony architecture and teeth are highly dependent to this ongoing procedure to maintain their functional form. Regarding the fundamental function of our skeletal system, all the involved components are at constant risk for injuries and deformations throughout the life. Therefore, in modern medicine, promotion of bone and tooth regeneration has become a critical counter measure to correct these acquired defects. There are numerous ways to address the bone and tooth related erosive pathologies but utilization of natural compounds has gained immense popularity in recent years. These materials provide a broad spectrum of therapeutic agents with a variety of biological characteristics. In this review, a comprehensive exploration has been implemented to extract and categorize the relevant scientific evidence on this issue, based on the source of natural candidates and the potential clinical indications. Database searching presented a considerable data pool with more than 300 references in this field. According to the results, all the proposed items can be categorized in two major groups including scaffolding and osteogenesis (or dentinogenesis) induction. The clinical applicability of a number of them is properly demonstrated in clinical trials but for the rest, more examinations are required to reach a conclusive decision.http://www.sciencedirect.com/science/article/pii/S2238785421005299NaturalBioactive materialsRegenerationBoneTooth |
| spellingShingle | Ehsan Tafazoli Moghadam Mohsen Yazdanian Mostafa Alam Hamid Tebyanian Ali Tafazoli Elahe Tahmasebi Reza Ranjbar Alireza Yazdanian Alexander Seifalian Current natural bioactive materials in bone and tooth regeneration in dentistry: a comprehensive overview Journal of Materials Research and Technology Natural Bioactive materials Regeneration Bone Tooth |
| title | Current natural bioactive materials in bone and tooth regeneration in dentistry: a comprehensive overview |
| title_full | Current natural bioactive materials in bone and tooth regeneration in dentistry: a comprehensive overview |
| title_fullStr | Current natural bioactive materials in bone and tooth regeneration in dentistry: a comprehensive overview |
| title_full_unstemmed | Current natural bioactive materials in bone and tooth regeneration in dentistry: a comprehensive overview |
| title_short | Current natural bioactive materials in bone and tooth regeneration in dentistry: a comprehensive overview |
| title_sort | current natural bioactive materials in bone and tooth regeneration in dentistry a comprehensive overview |
| topic | Natural Bioactive materials Regeneration Bone Tooth |
| url | http://www.sciencedirect.com/science/article/pii/S2238785421005299 |
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