Arene Ru(II) Complexes with Difluorinated Ligands Act as Potential Inducers of S-Phase Arrest via the Stabilization of <i>c-myc</i> G-Quadruplex DNA
Here, a series of half-sandwich arene Ru(II) complexes with difluorinated ligands [Ru(<i>η</i><sup>6</sup>-arene)(L)Cl] (<b>L</b><b><sub>1</sub></b> = 2-(2,3-difluorophenyl)imidazole[4,5<i>f</i>][1,10]-phenanthroline; <b>L...
Main Authors: | Liang Zeng, Chanling Yuan, Jing Shu, Jiayi Qian, Qiong Wu, Yanhua Chen, Ruzhen Wu, Xiaoming Ouyang, Yuan Li, Wenjie Mei |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-03-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/27/6/1897 |
Similar Items
-
Arene Ru(II) Complexes Acted as Potential <i>KRAS</i> G-Quadruplex DNA Stabilizer Induced DNA Damage Mediated Apoptosis to Inhibit Breast Cancer Progress
by: Jiayi Qian, et al.
Published: (2022-05-01) -
Novel Chiral Ru(II) Complexes as Potential c-myc G-quadruplex DNA Stabilizers Inducing DNA Damage to Suppress Triple-Negative Breast Cancer Progression
by: Chanling Yuan, et al.
Published: (2022-12-01) -
Catalytic, dearomative 2,3-difluorination of indoles
by: Fang-Hai Tu, et al.
Published: (2023-12-01) -
Itraconazole and Difluorinated-Curcumin Containing Chitosan Nanoparticle Loaded Hydrogel for Amelioration of Onychomycosis
by: Prashant Kesharwani, et al.
Published: (2022-11-01) -
Targeted Downregulation of MYC through G-quadruplex Stabilization by DNAi
by: Alexandra Maria Psaras, et al.
Published: (2021-09-01)