ANALGETIC ACTIVITY OF SUBSTITUTED 1-(2-IMIDAZOLETHYL)-3- PYRROLINE-2-ONS
The article presents the review of initial stage of carried out studies of an analgetic activity of substituted 1-(2-imidazolethyl)-3-pyrroline-2-ons. We have established that compound marked with laboratory cipher as GKN-1165 at a dose of 50 mg/kg has analgetic activity close to the activity of eth...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute
2015-09-01
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| Series: | Фармация и фармакология (Пятигорск) |
| Subjects: | |
| Online Access: | https://www.pharmpharm.ru/jour/article/view/79 |
| _version_ | 1797874777840418816 |
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| author | A. A. Ponomaryova A. S. Yurchenko N. N. Kasimova |
| author_facet | A. A. Ponomaryova A. S. Yurchenko N. N. Kasimova |
| author_sort | A. A. Ponomaryova |
| collection | DOAJ |
| description | The article presents the review of initial stage of carried out studies of an analgetic activity of substituted 1-(2-imidazolethyl)-3-pyrroline-2-ons. We have established that compound marked with laboratory cipher as GKN-1165 at a dose of 50 mg/kg has analgetic activity close to the activity of ethanol of nimesulid comparison taken at the same dose. |
| first_indexed | 2024-04-10T01:37:20Z |
| format | Article |
| id | doaj.art-c3987ca8f1664467b97512f90f19d6d0 |
| institution | Directory Open Access Journal |
| issn | 2307-9266 2413-2241 |
| language | Russian |
| last_indexed | 2024-04-10T01:37:20Z |
| publishDate | 2015-09-01 |
| publisher | Volgograd State Medical University, Pyatigorsk Medical and Pharmaceutical Institute |
| record_format | Article |
| series | Фармация и фармакология (Пятигорск) |
| spelling | doaj.art-c3987ca8f1664467b97512f90f19d6d02023-03-13T09:18:10ZrusVolgograd State Medical University, Pyatigorsk Medical and Pharmaceutical InstituteФармация и фармакология (Пятигорск)2307-92662413-22412015-09-0126(7)9910110.19163/2307-9266-2014-2-6(7)-99-10179ANALGETIC ACTIVITY OF SUBSTITUTED 1-(2-IMIDAZOLETHYL)-3- PYRROLINE-2-ONSA. A. Ponomaryova0A. S. Yurchenko1N. N. Kasimova2Пермская государственная фармацевтическая академия, г. ПермьПермская государственная фармацевтическая академия, г. ПермьПермская государственная фармацевтическая академия, г. ПермьThe article presents the review of initial stage of carried out studies of an analgetic activity of substituted 1-(2-imidazolethyl)-3-pyrroline-2-ons. We have established that compound marked with laboratory cipher as GKN-1165 at a dose of 50 mg/kg has analgetic activity close to the activity of ethanol of nimesulid comparison taken at the same dose.https://www.pharmpharm.ru/jour/article/view/79анальгетическая активностьзамещенные 1-(2-имидазолэтил)-3- пирролин-2-онынимесулидметодика «горячей пластинки». |
| spellingShingle | A. A. Ponomaryova A. S. Yurchenko N. N. Kasimova ANALGETIC ACTIVITY OF SUBSTITUTED 1-(2-IMIDAZOLETHYL)-3- PYRROLINE-2-ONS Фармация и фармакология (Пятигорск) анальгетическая активность замещенные 1-(2-имидазолэтил)-3- пирролин-2-оны нимесулид методика «горячей пластинки». |
| title | ANALGETIC ACTIVITY OF SUBSTITUTED 1-(2-IMIDAZOLETHYL)-3- PYRROLINE-2-ONS |
| title_full | ANALGETIC ACTIVITY OF SUBSTITUTED 1-(2-IMIDAZOLETHYL)-3- PYRROLINE-2-ONS |
| title_fullStr | ANALGETIC ACTIVITY OF SUBSTITUTED 1-(2-IMIDAZOLETHYL)-3- PYRROLINE-2-ONS |
| title_full_unstemmed | ANALGETIC ACTIVITY OF SUBSTITUTED 1-(2-IMIDAZOLETHYL)-3- PYRROLINE-2-ONS |
| title_short | ANALGETIC ACTIVITY OF SUBSTITUTED 1-(2-IMIDAZOLETHYL)-3- PYRROLINE-2-ONS |
| title_sort | analgetic activity of substituted 1 2 imidazolethyl 3 pyrroline 2 ons |
| topic | анальгетическая активность замещенные 1-(2-имидазолэтил)-3- пирролин-2-оны нимесулид методика «горячей пластинки». |
| url | https://www.pharmpharm.ru/jour/article/view/79 |
| work_keys_str_mv | AT aaponomaryova analgeticactivityofsubstituted12imidazolethyl3pyrroline2ons AT asyurchenko analgeticactivityofsubstituted12imidazolethyl3pyrroline2ons AT nnkasimova analgeticactivityofsubstituted12imidazolethyl3pyrroline2ons |