Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses
Jeffery Schafer,1 William Reindel,1 Robert Steffen,1 Gary Mosehauer,1 Joseph Chinn2 1Vision Care, Bausch and Lomb Incorporated, Rochester, NY, USA; 2J Chinn LLC, Lafayette, CO, USA Background: Sustained digital display viewing reduces eye blink frequency and tear film stability. To retain water an...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2018-05-01
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| Series: | Clinical Ophthalmology |
| Subjects: | |
| Online Access: | https://www.dovepress.com/use-of-a-novel-extended-blink-test-to-evaluate-the-performance-of-two--peer-reviewed-article-OPTH |
| _version_ | 1818845334058565632 |
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| author | Schafer J Reindel W Steffen R Mosehauer G Chinn J |
| author_facet | Schafer J Reindel W Steffen R Mosehauer G Chinn J |
| author_sort | Schafer J |
| collection | DOAJ |
| description | Jeffery Schafer,1 William Reindel,1 Robert Steffen,1 Gary Mosehauer,1 Joseph Chinn2 1Vision Care, Bausch and Lomb Incorporated, Rochester, NY, USA; 2J Chinn LLC, Lafayette, CO, USA Background: Sustained digital display viewing reduces eye blink frequency and tear film stability. To retain water and preserve a smooth optical surface, contact lens manufacturers have integrated the humectant polyvinylpyrrolidone (PVP) into silicone hydrogel contact lenses. In this study, extended blink time (EBT) was used to assess visual stability over a prolonged blink interval of two PVP-containing silicone hydrogel lenses, samfilcon A (SAM) and senofilcon A (SEN).Materials and methods: This randomized, bilateral, masked, crossover study assessed lens performance in ten subjects after 16 hours of wear. EBT, ie, the time elapsed between cessation of blinking and blur-out of a threshold letter on the acuity chart, was measured. At the end of the wear period, subjects reported duration of computer use and rated visual quality (VQ) and comfort while wearing the assigned lens, and the investigator evaluated lens surface wetting characteristics. Each lens was removed and immediately weighed to determine total water content.Results: EBTs were 10.42 seconds for SAM and 8.04 seconds for SEN (p = 0.015). Subjective ratings of VQ after 16 hours of wear were 84.6 for SAM and 74.4 for SEN (p = 0.049). Comfort ratings were 85.9 for SAM and 80.2 for SEN (p > 0.05). Median times of computer use were 6–8 hours for both lens types. Post blink, 70.0% of SAM and 30.0% of SEN lenses were completely wet (p = 0.021). Total water content after wear was 43.7% for SAM and 35.5% for SEN (p < 0.001).Conclusion: EBT measurement indicated more stable vision with the PVP-containing SAM polymer compared with the PVP-containing SEN polymer. The SAM polymer also demonstrated better surface wetting and maintained higher water content after a prolonged period of wear. EBT can be valuable in assessing vision stability of patients after hours of computer use. Keywords: polyvinylpyrrolidone, PVP, digital video display, extended blink time, EBT, visual quality, VQ, lens hydration |
| first_indexed | 2024-12-19T05:28:00Z |
| format | Article |
| id | doaj.art-c399917cc92542b2a612b4a8c3db7cd2 |
| institution | Directory Open Access Journal |
| issn | 1177-5483 |
| language | English |
| last_indexed | 2024-12-19T05:28:00Z |
| publishDate | 2018-05-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj.art-c399917cc92542b2a612b4a8c3db7cd22022-12-21T20:34:20ZengDove Medical PressClinical Ophthalmology1177-54832018-05-01Volume 1281982538109Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lensesSchafer JReindel WSteffen RMosehauer GChinn JJeffery Schafer,1 William Reindel,1 Robert Steffen,1 Gary Mosehauer,1 Joseph Chinn2 1Vision Care, Bausch and Lomb Incorporated, Rochester, NY, USA; 2J Chinn LLC, Lafayette, CO, USA Background: Sustained digital display viewing reduces eye blink frequency and tear film stability. To retain water and preserve a smooth optical surface, contact lens manufacturers have integrated the humectant polyvinylpyrrolidone (PVP) into silicone hydrogel contact lenses. In this study, extended blink time (EBT) was used to assess visual stability over a prolonged blink interval of two PVP-containing silicone hydrogel lenses, samfilcon A (SAM) and senofilcon A (SEN).Materials and methods: This randomized, bilateral, masked, crossover study assessed lens performance in ten subjects after 16 hours of wear. EBT, ie, the time elapsed between cessation of blinking and blur-out of a threshold letter on the acuity chart, was measured. At the end of the wear period, subjects reported duration of computer use and rated visual quality (VQ) and comfort while wearing the assigned lens, and the investigator evaluated lens surface wetting characteristics. Each lens was removed and immediately weighed to determine total water content.Results: EBTs were 10.42 seconds for SAM and 8.04 seconds for SEN (p = 0.015). Subjective ratings of VQ after 16 hours of wear were 84.6 for SAM and 74.4 for SEN (p = 0.049). Comfort ratings were 85.9 for SAM and 80.2 for SEN (p > 0.05). Median times of computer use were 6–8 hours for both lens types. Post blink, 70.0% of SAM and 30.0% of SEN lenses were completely wet (p = 0.021). Total water content after wear was 43.7% for SAM and 35.5% for SEN (p < 0.001).Conclusion: EBT measurement indicated more stable vision with the PVP-containing SAM polymer compared with the PVP-containing SEN polymer. The SAM polymer also demonstrated better surface wetting and maintained higher water content after a prolonged period of wear. EBT can be valuable in assessing vision stability of patients after hours of computer use. Keywords: polyvinylpyrrolidone, PVP, digital video display, extended blink time, EBT, visual quality, VQ, lens hydrationhttps://www.dovepress.com/use-of-a-novel-extended-blink-test-to-evaluate-the-performance-of-two--peer-reviewed-article-OPTHpolyvinylpyrrolidone (PVP)digital video displayextended blink time (EBT)visual quality (VQ)lens hydration |
| spellingShingle | Schafer J Reindel W Steffen R Mosehauer G Chinn J Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses Clinical Ophthalmology polyvinylpyrrolidone (PVP) digital video display extended blink time (EBT) visual quality (VQ) lens hydration |
| title | Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses |
| title_full | Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses |
| title_fullStr | Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses |
| title_full_unstemmed | Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses |
| title_short | Use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone-containing, silicone hydrogel contact lenses |
| title_sort | use of a novel extended blink test to evaluate the performance of two polyvinylpyrrolidone containing silicone hydrogel contact lenses |
| topic | polyvinylpyrrolidone (PVP) digital video display extended blink time (EBT) visual quality (VQ) lens hydration |
| url | https://www.dovepress.com/use-of-a-novel-extended-blink-test-to-evaluate-the-performance-of-two--peer-reviewed-article-OPTH |
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