In-target production of [11C]CH4 from a nitrogen/hydrogen gas target as a function of beam current, irradiation time, and target temperature

In-target production of [11C]CH4 from a nitrogen/hydrogen gas target as a function of beam current, irradiation time, and target temperature

Abstract Background Production of [11C]CH4 from gas targets is notorious for weak performance with respect to yield, especially when using high beam currents. Post-target conversion of [11C]CO2 to [11C]CH4 is a widely used roundabout method in 11C-radiochemistry, but the added complexity increase th...

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Bibliographic Details
Main Authors: Semi Helin, Johan Rajander, Jussi Aromaa, Eveliina Arponen, Jatta S. Helin, Olof Solin
Format: Article
Language:English
Published: SpringerOpen 2024-03-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Carbon-11
[11C]methane
Targetry
PET
Haber–Bosch
Online Access:https://doi.org/10.1186/s41181-024-00255-1

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