CircZSWIM6 mediates dysregulation of ECM and energy homeostasis in ageing chondrocytes through RPS14 post‐translational modification

CircZSWIM6 mediates dysregulation of ECM and energy homeostasis in ageing chondrocytes through RPS14 post‐translational modification

Abstract Background Circular RNAs (CircRNAs) are important and have different roles in disease progression. Herein, we aim to elucidate the roles of a novel CircRNA (CircZSWIM6) which is upregulated in ageing chondrocytes. Methods We verified the roles of CircZSWIM6 in senescent and osteoarthritis (...

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Bibliographic Details
Main Authors: Zhe Gong, Kefan Wang, Junxin Chen, Jinjin Zhu, Zhenhua Feng, Chenxin Song, Zheyuan Zhang, Haoming Wang, Shunwu Fan, Shuying Shen, Xiangqian Fang
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Clinical and Translational Medicine
Subjects:
AMPK
CircZSWIM6
metabolism
osteoarthritis
RPS14
senescence
Online Access:https://doi.org/10.1002/ctm2.1158

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