The autologous platelet rich fibrin: A novel approach in osseous regeneration after cystic enucleation: A pilot study

Context: The platelet rich fibrin (PRF) is second generation platelet concentrate that has been widely used and researched for stimulation and acceleration of soft tissue and osseous healing. Its continuous delivery of growth factors and proteins mimic the need of physiological wound healing and reg...

Full description

Bibliographic Details
Main Authors: Vikas Sukhadeo Meshram, Pravin Narendra Lambade, Priyatama Vikas Meshram, Aishwarya Kadu, Manish Sevalal Tiwari
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Indian Journal of Dental Research
Subjects:
Online Access:http://www.ijdr.in/article.asp?issn=0970-9290;year=2015;volume=26;issue=6;spage=560;epage=564;aulast=Meshram
_version_ 1811308334343520256
author Vikas Sukhadeo Meshram
Pravin Narendra Lambade
Priyatama Vikas Meshram
Aishwarya Kadu
Manish Sevalal Tiwari
author_facet Vikas Sukhadeo Meshram
Pravin Narendra Lambade
Priyatama Vikas Meshram
Aishwarya Kadu
Manish Sevalal Tiwari
author_sort Vikas Sukhadeo Meshram
collection DOAJ
description Context: The platelet rich fibrin (PRF) is second generation platelet concentrate that has been widely used and researched for stimulation and acceleration of soft tissue and osseous healing. Its continuous delivery of growth factors and proteins mimic the need of physiological wound healing and regenerative tissue processes. Aims and Objectives: The aim of this study was to evaluate the efficacy of PRF in osseous regeneration after enucleation of cystic lesions. The objectives of this study were: (1) To evaluate osseous regeneration radiographically with the use of PRF in intrabony defects after cystic enucleation. (2) To evaluate the degree of bone density in intrabony defects with the use of PRF postoperatively after 1 st , 3 rd , and 6 th months. Subjects and Methods: 10 cases of cystic lesions were treated using PRF after cystic enucleation. Follow-up radiographs (orthopantomogram) were taken 1 st , 3 rd , and 6 th months postoperatively. Bone density was measured with grayscale histogram using Adobe Photoshop 7.0 software. Results: The subsequent follow-up examinations revealed progressive, predictable, and significant radiographic osseous regeneration. Conclusion: The use of PRF in management of cystic lesions seems to be a novel therapeutic approach promoting faster osseous regeneration within 6 months postoperatively however further study is required with larger sample size and with a control group.
first_indexed 2024-04-13T09:21:23Z
format Article
id doaj.art-c3a92bd0891d47cfaaed98cf2195c5d4
institution Directory Open Access Journal
issn 0970-9290
1998-3603
language English
last_indexed 2024-04-13T09:21:23Z
publishDate 2015-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Indian Journal of Dental Research
spelling doaj.art-c3a92bd0891d47cfaaed98cf2195c5d42022-12-22T02:52:36ZengWolters Kluwer Medknow PublicationsIndian Journal of Dental Research0970-92901998-36032015-01-0126656056410.4103/0970-9290.176915The autologous platelet rich fibrin: A novel approach in osseous regeneration after cystic enucleation: A pilot studyVikas Sukhadeo MeshramPravin Narendra LambadePriyatama Vikas MeshramAishwarya KaduManish Sevalal TiwariContext: The platelet rich fibrin (PRF) is second generation platelet concentrate that has been widely used and researched for stimulation and acceleration of soft tissue and osseous healing. Its continuous delivery of growth factors and proteins mimic the need of physiological wound healing and regenerative tissue processes. Aims and Objectives: The aim of this study was to evaluate the efficacy of PRF in osseous regeneration after enucleation of cystic lesions. The objectives of this study were: (1) To evaluate osseous regeneration radiographically with the use of PRF in intrabony defects after cystic enucleation. (2) To evaluate the degree of bone density in intrabony defects with the use of PRF postoperatively after 1 st , 3 rd , and 6 th months. Subjects and Methods: 10 cases of cystic lesions were treated using PRF after cystic enucleation. Follow-up radiographs (orthopantomogram) were taken 1 st , 3 rd , and 6 th months postoperatively. Bone density was measured with grayscale histogram using Adobe Photoshop 7.0 software. Results: The subsequent follow-up examinations revealed progressive, predictable, and significant radiographic osseous regeneration. Conclusion: The use of PRF in management of cystic lesions seems to be a novel therapeutic approach promoting faster osseous regeneration within 6 months postoperatively however further study is required with larger sample size and with a control group.http://www.ijdr.in/article.asp?issn=0970-9290;year=2015;volume=26;issue=6;spage=560;epage=564;aulast=MeshramCystic lesionshistogramosseous regenerationplatelet rich fibrin
spellingShingle Vikas Sukhadeo Meshram
Pravin Narendra Lambade
Priyatama Vikas Meshram
Aishwarya Kadu
Manish Sevalal Tiwari
The autologous platelet rich fibrin: A novel approach in osseous regeneration after cystic enucleation: A pilot study
Indian Journal of Dental Research
Cystic lesions
histogram
osseous regeneration
platelet rich fibrin
title The autologous platelet rich fibrin: A novel approach in osseous regeneration after cystic enucleation: A pilot study
title_full The autologous platelet rich fibrin: A novel approach in osseous regeneration after cystic enucleation: A pilot study
title_fullStr The autologous platelet rich fibrin: A novel approach in osseous regeneration after cystic enucleation: A pilot study
title_full_unstemmed The autologous platelet rich fibrin: A novel approach in osseous regeneration after cystic enucleation: A pilot study
title_short The autologous platelet rich fibrin: A novel approach in osseous regeneration after cystic enucleation: A pilot study
title_sort autologous platelet rich fibrin a novel approach in osseous regeneration after cystic enucleation a pilot study
topic Cystic lesions
histogram
osseous regeneration
platelet rich fibrin
url http://www.ijdr.in/article.asp?issn=0970-9290;year=2015;volume=26;issue=6;spage=560;epage=564;aulast=Meshram
work_keys_str_mv AT vikassukhadeomeshram theautologousplateletrichfibrinanovelapproachinosseousregenerationaftercysticenucleationapilotstudy
AT pravinnarendralambade theautologousplateletrichfibrinanovelapproachinosseousregenerationaftercysticenucleationapilotstudy
AT priyatamavikasmeshram theautologousplateletrichfibrinanovelapproachinosseousregenerationaftercysticenucleationapilotstudy
AT aishwaryakadu theautologousplateletrichfibrinanovelapproachinosseousregenerationaftercysticenucleationapilotstudy
AT manishsevalaltiwari theautologousplateletrichfibrinanovelapproachinosseousregenerationaftercysticenucleationapilotstudy
AT vikassukhadeomeshram autologousplateletrichfibrinanovelapproachinosseousregenerationaftercysticenucleationapilotstudy
AT pravinnarendralambade autologousplateletrichfibrinanovelapproachinosseousregenerationaftercysticenucleationapilotstudy
AT priyatamavikasmeshram autologousplateletrichfibrinanovelapproachinosseousregenerationaftercysticenucleationapilotstudy
AT aishwaryakadu autologousplateletrichfibrinanovelapproachinosseousregenerationaftercysticenucleationapilotstudy
AT manishsevalaltiwari autologousplateletrichfibrinanovelapproachinosseousregenerationaftercysticenucleationapilotstudy