AMINO ACID SEQUENCE MOTIVE OF OSELTAMIVIR BINDING POCKET IN NEURAMINIDASE PROTEIN OF AVIAN INFLUENZA (H5N1) VIRUS FROM HUMAN AND ANIMAL IN INDONESIA
<span style="color: #29363d; font-family: Tahoma, Arial, Helvetica, sans-serif; font-size: 14px; font-style: italic; text-align: justify; background-color: #ddeaf4;">Former finding that avian influenza (AI) virus of H5N1 subtype from Indonesia shows reduced sensitivity against oselta...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Universitas Udayana
2008-12-01
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| Series: | Jurnal Veteriner |
| Online Access: | http://ojs.unud.ac.id/index.php/jvet/article/view/3336 |
| _version_ | 1818981113443385344 |
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| author | I Gusti Ngurah Kade Mahardika I Made Sukada Made Suma Antara I Gusti Ayu Suartini |
| author_facet | I Gusti Ngurah Kade Mahardika I Made Sukada Made Suma Antara I Gusti Ayu Suartini |
| author_sort | I Gusti Ngurah Kade Mahardika |
| collection | DOAJ |
| description | <span style="color: #29363d; font-family: Tahoma, Arial, Helvetica, sans-serif; font-size: 14px; font-style: italic; text-align: justify; background-color: #ddeaf4;">Former finding that avian influenza (AI) virus of H5N1 subtype from Indonesia shows reduced sensitivity against oseltamivir is critically reviewed trough molecular observation of the amino-acid sequence motive of neuraminidase protein (NA) of all H5N1 virus from human and animal in Indonesia available in GeneBank. Amino acid sequence of oseltamivir binding pocket of NA protein on all Indonesian viruses is typical for sensitive virus with a concerved motive of H274, E276, R292 dan N294. Resistance issue could not be explained based on available data.</span><div><span style="color: #29363d; font-family: Tahoma, Arial, Helvetica, sans-serif; font-size: 14px; font-style: italic; text-align: justify; background-color: #ddeaf4;"><br /></span></div> |
| first_indexed | 2024-12-20T17:26:09Z |
| format | Article |
| id | doaj.art-c3ab5042eaeb486bbbbdffa0d7c34a9f |
| institution | Directory Open Access Journal |
| issn | 1411-8327 2477-5665 |
| language | English |
| last_indexed | 2024-12-20T17:26:09Z |
| publishDate | 2008-12-01 |
| publisher | Universitas Udayana |
| record_format | Article |
| series | Jurnal Veteriner |
| spelling | doaj.art-c3ab5042eaeb486bbbbdffa0d7c34a9f2022-12-21T19:31:35ZengUniversitas UdayanaJurnal Veteriner1411-83272477-56652008-12-01943170AMINO ACID SEQUENCE MOTIVE OF OSELTAMIVIR BINDING POCKET IN NEURAMINIDASE PROTEIN OF AVIAN INFLUENZA (H5N1) VIRUS FROM HUMAN AND ANIMAL IN INDONESIAI Gusti Ngurah Kade MahardikaI Made SukadaMade Suma AntaraI Gusti Ayu Suartini<span style="color: #29363d; font-family: Tahoma, Arial, Helvetica, sans-serif; font-size: 14px; font-style: italic; text-align: justify; background-color: #ddeaf4;">Former finding that avian influenza (AI) virus of H5N1 subtype from Indonesia shows reduced sensitivity against oseltamivir is critically reviewed trough molecular observation of the amino-acid sequence motive of neuraminidase protein (NA) of all H5N1 virus from human and animal in Indonesia available in GeneBank. Amino acid sequence of oseltamivir binding pocket of NA protein on all Indonesian viruses is typical for sensitive virus with a concerved motive of H274, E276, R292 dan N294. Resistance issue could not be explained based on available data.</span><div><span style="color: #29363d; font-family: Tahoma, Arial, Helvetica, sans-serif; font-size: 14px; font-style: italic; text-align: justify; background-color: #ddeaf4;"><br /></span></div>http://ojs.unud.ac.id/index.php/jvet/article/view/3336 |
| spellingShingle | I Gusti Ngurah Kade Mahardika I Made Sukada Made Suma Antara I Gusti Ayu Suartini AMINO ACID SEQUENCE MOTIVE OF OSELTAMIVIR BINDING POCKET IN NEURAMINIDASE PROTEIN OF AVIAN INFLUENZA (H5N1) VIRUS FROM HUMAN AND ANIMAL IN INDONESIA Jurnal Veteriner |
| title | AMINO ACID SEQUENCE MOTIVE OF OSELTAMIVIR BINDING POCKET IN NEURAMINIDASE PROTEIN OF AVIAN INFLUENZA (H5N1) VIRUS FROM HUMAN AND ANIMAL IN INDONESIA |
| title_full | AMINO ACID SEQUENCE MOTIVE OF OSELTAMIVIR BINDING POCKET IN NEURAMINIDASE PROTEIN OF AVIAN INFLUENZA (H5N1) VIRUS FROM HUMAN AND ANIMAL IN INDONESIA |
| title_fullStr | AMINO ACID SEQUENCE MOTIVE OF OSELTAMIVIR BINDING POCKET IN NEURAMINIDASE PROTEIN OF AVIAN INFLUENZA (H5N1) VIRUS FROM HUMAN AND ANIMAL IN INDONESIA |
| title_full_unstemmed | AMINO ACID SEQUENCE MOTIVE OF OSELTAMIVIR BINDING POCKET IN NEURAMINIDASE PROTEIN OF AVIAN INFLUENZA (H5N1) VIRUS FROM HUMAN AND ANIMAL IN INDONESIA |
| title_short | AMINO ACID SEQUENCE MOTIVE OF OSELTAMIVIR BINDING POCKET IN NEURAMINIDASE PROTEIN OF AVIAN INFLUENZA (H5N1) VIRUS FROM HUMAN AND ANIMAL IN INDONESIA |
| title_sort | amino acid sequence motive of oseltamivir binding pocket in neuraminidase protein of avian influenza h5n1 virus from human and animal in indonesia |
| url | http://ojs.unud.ac.id/index.php/jvet/article/view/3336 |
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