Cancer Diagnosis Using Terahertz-Graphene-Metasurface-Based Biosensor with Dual-Resonance Response
Owing to the outstanding physical properties of graphene, its biosensing applications implemented by the terahertz metasurface are widely concerned and studied. Here, we present a novel design of the graphene metasurface, which consists of an individual graphene ring and an H-shaped graphene structu...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/12/21/3889 |
| _version_ | 1797467002624802816 |
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| author | Chunjian Tan Shaogang Wang Shizhen Li Xu Liu Jia Wei Guoqi Zhang Huaiyu Ye |
| author_facet | Chunjian Tan Shaogang Wang Shizhen Li Xu Liu Jia Wei Guoqi Zhang Huaiyu Ye |
| author_sort | Chunjian Tan |
| collection | DOAJ |
| description | Owing to the outstanding physical properties of graphene, its biosensing applications implemented by the terahertz metasurface are widely concerned and studied. Here, we present a novel design of the graphene metasurface, which consists of an individual graphene ring and an H-shaped graphene structure. The graphene metasurface exhibits a dual-resonance response, whose resonance frequency strongly varies with the geometrical parameters of the proposed metasurface, the carrier density of graphene, and the analyte composition. The transparency window, including width and position, can be artificially controlled by adjusting the geometrical parameters or the Fermi energy. Furthermore, the sensing parameters of the graphene metasurface for cancerous and normal cells are investigated, focusing on two factors, namely cell quantity and position on the metasurface. The simulated results clearly show that the theoretical sensitivity, figure of merit, and quantity of the graphene metasurface for breast cells reach 1.21 THz/RIU, 2.75 RIU<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mrow></mrow><mrow><mo>−</mo><mn>1</mn></mrow></msup></semantics></math></inline-formula>, and 2.43, respectively. Our findings may open up new avenues for promising applications in the diagnosis of cancers. |
| first_indexed | 2024-03-09T18:47:21Z |
| format | Article |
| id | doaj.art-c3afdc58dc694a3f9f9014b8ae3f6251 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-09T18:47:21Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-c3afdc58dc694a3f9f9014b8ae3f62512023-11-24T06:10:52ZengMDPI AGNanomaterials2079-49912022-11-011221388910.3390/nano12213889Cancer Diagnosis Using Terahertz-Graphene-Metasurface-Based Biosensor with Dual-Resonance ResponseChunjian Tan0Shaogang Wang1Shizhen Li2Xu Liu3Jia Wei4Guoqi Zhang5Huaiyu Ye6Electronic Components, Technology and Materials, Delft University of Technology, 2628 CD Delft, The NetherlandsElectronic Components, Technology and Materials, Delft University of Technology, 2628 CD Delft, The NetherlandsEngineering Research Center of Integrated Circuits for Next-Generation Communications, Ministry of Education, School of Microelectronics, Southern University of Science and Technology, Shenzhen 518055, ChinaElectronic Components, Technology and Materials, Delft University of Technology, 2628 CD Delft, The NetherlandsBioland Laboratory, Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou 510005, ChinaElectronic Components, Technology and Materials, Delft University of Technology, 2628 CD Delft, The NetherlandsEngineering Research Center of Integrated Circuits for Next-Generation Communications, Ministry of Education, School of Microelectronics, Southern University of Science and Technology, Shenzhen 518055, ChinaOwing to the outstanding physical properties of graphene, its biosensing applications implemented by the terahertz metasurface are widely concerned and studied. Here, we present a novel design of the graphene metasurface, which consists of an individual graphene ring and an H-shaped graphene structure. The graphene metasurface exhibits a dual-resonance response, whose resonance frequency strongly varies with the geometrical parameters of the proposed metasurface, the carrier density of graphene, and the analyte composition. The transparency window, including width and position, can be artificially controlled by adjusting the geometrical parameters or the Fermi energy. Furthermore, the sensing parameters of the graphene metasurface for cancerous and normal cells are investigated, focusing on two factors, namely cell quantity and position on the metasurface. The simulated results clearly show that the theoretical sensitivity, figure of merit, and quantity of the graphene metasurface for breast cells reach 1.21 THz/RIU, 2.75 RIU<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msup><mrow></mrow><mrow><mo>−</mo><mn>1</mn></mrow></msup></semantics></math></inline-formula>, and 2.43, respectively. Our findings may open up new avenues for promising applications in the diagnosis of cancers.https://www.mdpi.com/2079-4991/12/21/3889graphene metasurfaceterahertz sensingdual-resonance responsecancer diagnosis |
| spellingShingle | Chunjian Tan Shaogang Wang Shizhen Li Xu Liu Jia Wei Guoqi Zhang Huaiyu Ye Cancer Diagnosis Using Terahertz-Graphene-Metasurface-Based Biosensor with Dual-Resonance Response Nanomaterials graphene metasurface terahertz sensing dual-resonance response cancer diagnosis |
| title | Cancer Diagnosis Using Terahertz-Graphene-Metasurface-Based Biosensor with Dual-Resonance Response |
| title_full | Cancer Diagnosis Using Terahertz-Graphene-Metasurface-Based Biosensor with Dual-Resonance Response |
| title_fullStr | Cancer Diagnosis Using Terahertz-Graphene-Metasurface-Based Biosensor with Dual-Resonance Response |
| title_full_unstemmed | Cancer Diagnosis Using Terahertz-Graphene-Metasurface-Based Biosensor with Dual-Resonance Response |
| title_short | Cancer Diagnosis Using Terahertz-Graphene-Metasurface-Based Biosensor with Dual-Resonance Response |
| title_sort | cancer diagnosis using terahertz graphene metasurface based biosensor with dual resonance response |
| topic | graphene metasurface terahertz sensing dual-resonance response cancer diagnosis |
| url | https://www.mdpi.com/2079-4991/12/21/3889 |
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