A new method for detection of <it>pfmdr1 </it>mutations in <it>Plasmodium falciparum </it>DNA using real-time PCR

A new method for detection of <it>pfmdr1 </it>mutations in <it>Plasmodium falciparum </it>DNA using real-time PCR

<p>Abstract</p> <p>Background</p> <p>Surveillance for drug-resistant <it>Plasmodium falciparum </it>should be a component of malaria control programmes. Real-time PCR methods for the detection of parasite single-nucleotide polymorphisms (SNPs) and gene ampli...

Full description

Bibliographic Details
Main Authors:	Welch Kathy, Miller R Scott, McDaniel Phillip, Congpuong Kanungnij, Laoboonchai Anita, Nelson Amy, Purfield Anne, Wongsrichanalai Chansuda, Meshnick Steven R
Format:	Article
Language:	English
Published:	BMC 2004-05-01
Series:	Malaria Journal
Online Access:	http://www.malariajournal.com/content/3/1/9

Similar Items

<it>Pfmdr1 </it>copy number and arteminisin derivatives combination therapy failure in falciparum malaria in Cambodia
by: Wongsrichanalai Chansuda, et al.
Published: (2009-01-01)

Delayed <it>Plasmodium falciparum</it> clearance following artesunate-mefloquine combination therapy in Thailand, 1997–2007
by: Vijaykadga Saowanit, et al.
Published: (2012-08-01)

Molecular Surveillance for Multidrug-Resistant Plasmodium falciparum, Cambodia
by: Naman K. Shah, et al.
Published: (2008-10-01)

Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number.
by: Price, R, et al.
Published: (2004)

Plasmodium falciparum pfmdr1 amplification, mefloquine resistance, and parasite fitness.
by: Preechapornkul, P, et al.
Published: (2009)

pfmdr1 amplification is related to increased Plasmodium falciparum in vitro sensitivity to the bisquinoline piperaquine.
by: Veiga, M, et al.
Published: (2012)

Origin and evolution of sulfadoxine resistant Plasmodium falciparum.
by: Sumiti Vinayak, et al.
Published: (2010-03-01)

Intrahost selection of Plasmodium falciparum pfmdr1 alleles after antimalarial treatment on the northwestern border of Thailand.
by: Uhlemann, A, et al.
Published: (2007)

K13 mutations and pfmdr1 copy number variation in Plasmodium falciparum malaria in Myanmar
by: Win, AA, et al.
Published: (2016)

Role of different Pfcrt and Pfmdr-1 mutations in conferring resistance to antimalaria drugs in Plasmodium falciparum
by: Ibraheem, Zaid O., et al.
Published: (2014)

Balanced impacts of fitness and drug pressure on the evolution of PfMDR1 polymorphisms in Plasmodium falciparum
by: Marvin Duvalsaint, et al.
Published: (2021-06-01)

Prevalence of Plasmodium falciparum Pfcrt and Pfmdr1 alleles in settings with different levels of Plasmodium vivax co-endemicity in Ethiopia
by: Elifaged Hailemeskel, et al.
Published: (2019-12-01)

Different patterns of pfcrt and pfmdr1 polymorphism in Plasmodium falciparum isolates from Tehama region, Yemen
by: Atroosh, Wahib M., et al.
Published: (2016)

Different patterns of pfcrt and pfmdr1 polymorphism in Plasmodium falciparum isolates from Tehama region, Yemen
by: Wahib M. Atroosh, et al.
Published: (2016-07-01)

Streamlined, PCR-based testing for pfhrp2- and pfhrp3-negative Plasmodium falciparum
by: Jonathan B. Parr, et al.
Published: (2018-04-01)

The pfmdr1 gene is associated with a multidrug-resistant phenotype in Plasmodium falciparum from the western border of Thailand.
by: Price, R, et al.
Published: (1999)

In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1.
by: Mwai, L, et al.
Published: (2009)

Pfcrt and pfmdr1 alleles associated with chloroquine resistance in Plasmodium falciparum from Guyana, South America
by: Wallis Best Plummer, et al.
Published: (2004-06-01)

Genetic polymorphisms in Plasmodium falciparum chloroquine resistance genes, pfcrt and pfmdr1, in North Sulawesi, Indonesia
by: Patrick Reteng, et al.
Published: (2017-04-01)

Efficacy of Artemether-Lumefantrine on various Plasmodium falciparum Kelch 13 and Pfmdr1 genes isolated in Ghana
by: Enoch Aninagyei, et al.
Published: (2020-11-01)

Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies
by: M. Isabel Veiga, et al.
Published: (2016-05-01)

Polymorphisms of the <it>pfmdr1 </it>but not the <it>pfnhe-1 </it>gene is associated with <it>in vitro </it>quinine sensitivity in Thai isolates of <it>Plasmodium falciparum</it>
by: Poyomtip Teera, et al.
Published: (2012-01-01)

Dual fluorescent labelling of the human malaria parasite <it>Plasmodium falciparum</it> for the analysis of the ABC type transporter <it>pfmdr2</it>
by: Rosental Benyamin, et al.
Published: (2012-11-01)

Prevalence of arps10, fd, pfmdr-2, pfcrt and pfkelch13 gene mutations in Plasmodium falciparum parasite population in Uganda.
by: Moses Ocan, et al.
Published: (2022-01-01)

Plasmodium falciparum drug resistance phenotype as assessed by patient antimalarial drug levels and its association with pfmdr1 polymorphisms.
by: Malmberg, M, et al.
Published: (2013)

Sequence analysis of coding DNA fragments of pfcrt and pfmdr-1 genes in Plasmodium falciparum isolates from Odisha, India
by: Sasmita Kumari Das Sutar, et al.
Published: (2011-02-01)

Plasmodium falciparum Drug Resistance Genes pfmdr1 and pfcrt In Vivo Co-Expression During Artemether-Lumefantrine Therapy
by: M. Silva, et al.
Published: (2022-05-01)

Evidence for linkage of pfmdr1, pfcrt, and pfk13 polymorphisms to lumefantrine and mefloquine susceptibilities in a Plasmodium falciparum cross
by: Sean T. Windle, et al.
Published: (2020-12-01)

PfMDR1 Transport Rates Assessed in Intact Isolated <i>Plasmodium falciparum</i> Digestive Vacuoles Reflect Functional Drug Resistance Relationship with <i>pfmdr1</i> Mutations
by: Nina Simon, et al.
Published: (2022-02-01)

Analisis PCR-SSCP Fragmen Gen pfmdr-1 Plasmodium isolat Kecamatan Tombatu, Kabupaten Minahasa Selatan, Propinsi Sulawesi Utara yang Resisten Terhadap Klorokuin = PCR-SSCP Analysis of pfmdr-1 Gene of ...
by: Perpustakaan UGM, i-lib
Published: (2006)

Directional selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu Loci of Plasmodium falciparum in Kenyan children treated With ACT
by: Henriques, G, et al.
Published: (2014)

Molecular surveillance of pfcrt, pfmdr1 and pfk13-propeller mutations in Plasmodium falciparum isolates imported from Africa to China
by: Fang Huang, et al.
Published: (2021-02-01)

Single nucleotide polymorphisms in Plasmodium falciparum V type H(+) pyrophosphatase gene (pfvp2) and their associations with pfcrt and pfmdr1 polymorphisms.
by: Jovel, I, et al.
Published: (2014)

Selection of Plasmodium falciparum pfcrt and pfmdr1 polymorphisms after treatment with artesunate-amodiaquine fixed dose combination or artemether-lumefantrine in Liberia
by: Otienoburu, SD, et al.
Published: (2016)

Single nucleotide polymorphisms in Plasmodium falciparum V type H(+) pyrophosphatase gene (pfvp2) and their associations with pfcrt and pfmdr1 polymorphisms
by: Jovel, Irina Tatiana, et al.
Published: (2014)

Differential Prevalences of Pfmdr1 Polymorphisms in Symptomatic and Asymptomatic Plasmodium falciparum Infections in Lastoursville: A Rural Area in East-Central Gabon
by: Ontoua SS, et al.
Published: (2021-07-01)

Artemether resistance <it>in vitro</it> is linked to mutations in PfATP6 that also interact with mutations in PfMDR1 in travellers returning with <it>Plasmodium falciparum</it> infections
by: Pillai Dylan R, et al.
Published: (2012-04-01)

Rapid detection of Pfcrt and Pfmdr1 mutations in <it>Plasmodium falciparum </it>isolates by FRET and <it>in vivo </it>response to chloroquine among children from Osogbo, Nigeria
by: Fendel Rolf, et al.
Published: (2007-04-01)

Markers of anti-malarial drug resistance in <it>Plasmodium falciparum </it>isolates from Swaziland: identification of <it>pfmdr1</it>-86F in natural parasite isolates
by: Beshir Khalid, et al.
Published: (2010-03-01)

Assessment of Plasmodium falciparum anti-malarial drug resistance markers in pfcrt and pfmdr1 genes in isolates from Honduras and Nicaragua, 2018–2021
by: Gustavo Fontecha, et al.
Published: (2021-12-01)