Teicoplanin-Modified HPLC Column as a Source of Experimental Parameters for Prediction of the Anticonvulsant Activity of 1,2,4-Triazole-3-Thiones by the Regression Models

Teicoplanin-Modified HPLC Column as a Source of Experimental Parameters for Prediction of the Anticonvulsant Activity of 1,2,4-Triazole-3-Thiones by the Regression Models

The cell membrane is a complex system that consists of lipids, proteins, polysaccharides, and amphiphilic phospholipids. It plays an important role in ADME processes that are responsible for the final pharmaceutical effects of xenobiotics (bioavailability, activity). To study drug-membrane interacti...

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Bibliographic Details
Main Authors: Jolanta Flieger, Anna Orzeł, Anna Kowalska-Kępczyńska, Magdalena Pizoń, Hanna Trębacz, Dariusz Majerek, Tomasz Plech, Wojciech Płaziński
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Materials
Subjects:
teicoplanin column
retention behavior
van’t Hoff relationship
phase ratio
phase transition
thermodynamic parameters
Online Access:https://www.mdpi.com/1996-1944/13/11/2650

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