V-Set and immunoglobulin domain containing (VSIG) proteins as emerging immune checkpoint targets for cancer immunotherapy

V-Set and immunoglobulin domain containing (VSIG) proteins as emerging immune checkpoint targets for cancer immunotherapy

The development of immune checkpoint inhibitors is becoming a promising approach to fight cancers. Antibodies targeting immune checkpoint proteins such as CTLA-4 and PD-1 can reinvigorate endogenous antitumor T-cell responses and bring durable advantages to several malignancies. However, only a smal...

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Bibliographic Details
Main Authors: Xia Zhou, Sohail Khan, Dabing Huang, Lu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Immunology
Subjects:
immune checkpoint
VSIG4/CRIg
VSIG
TIGIT
cancer immunotherapy
antitumor T-cell response
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.938470/full

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