Early and differential autoimmune diseases diagnosis by interrogating specific autoantibody signatures with multiplexed electrochemical bioplatforms

Early and differential autoimmune diseases diagnosis by interrogating specific autoantibody signatures with multiplexed electrochemical bioplatforms

This work reports the first bioplatform to assist in the early and reliable diagnosis of autoimmune diseases by quadruple determination of autoantibodies (Abs) produced against extractable nuclear antigens (ENAs): La/SSB-Abs, Ro/SSA-Abs, U1snRNP70-Abs and smRNP-Abs. The bioplatform involves indirect...

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Bibliographic Details
Main Authors: Beatriz Arévalo, Verónica Serafín, María Garranzo-Asensio, Rodrigo Barderas, Paloma Yáñez-Sedeño, Susana Campuzano, José M. Pingarrón
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Biosensors and Bioelectronics: X
Subjects:
ENAs-Abs
Quadruple electrochemical bioplatform
Magnetic beads
Screen-printed electrodes
Autoimmune diseases
Serum
Online Access:http://www.sciencedirect.com/science/article/pii/S2590137023000225

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