Determination of Chemical Irritation Potential Using a Defined Gene Signature Set on Tissue-Engineered Human Skin Equivalents

There are no physical or visual manifestations that define skin sensitivity or irritation; a subjective diagnosis is made on the basis of the evaluation of clinical presentations, including burning, prickling, erythema, and itching. Adverse skin reaction in response to topically applied products is...

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Bibliographic Details
Main Authors: Amy L. Harding, Craig Murdoch, Simon Danby, Md Zobaer Hasan, Hirofumi Nakanishi, Tetsuo Furuno, Sirwan Hadad, Robert Turner, Helen E. Colley
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:JID Innovations
Online Access:http://www.sciencedirect.com/science/article/pii/S2667026721000114