Formulation of Miconazole-Loaded Chitosan–Carbopol Vesicular Gel: Optimization to In Vitro Characterization, Irritation, and Antifungal Assessment

Formulation of Miconazole-Loaded Chitosan–Carbopol Vesicular Gel: Optimization to In Vitro Characterization, Irritation, and Antifungal Assessment

Miconazole nitrate (MN) is a poorly water-soluble and antifungal drug used for fungal infections. The present research work was designed to develop topical MN-loaded bilosomes (BSs) for the improvement of therapeutic efficacy. MZBSs were prepared by using the thin-film hydration method and further o...

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Bibliographic Details
Main Authors: Syed Sarim Imam, Sadaf Jamal Gilani, Ameeduzzafar Zafar, May Nasser Bin Jumah, Sultan Alshehri
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
miconazole nitrate
bilosome
gel
irritation study
antifungal activity
Online Access:https://www.mdpi.com/1999-4923/15/2/581

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