COVID-19 Mediated by Basigin Can Affect Male and Female Fertility

Coronavirus disease 2019 (COVID-19) prevalence has caused many problems in society and disrupted manyregular aspects of life. COVID-19 contains major structural proteins that among them, S protein can promotefusion of the viral and cellular membranes and facilitate the entry of coronavirus into the...

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Main Authors: Soodeh Mahdian, Maryam Shahhoseini, Ashraf Moini
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2020-10-01
Series:International Journal of Fertility and Sterility
Subjects:
Online Access:http://www.ijfs.ir/article_45674_f571c3e965f0662181f09336570aec5a.pdf
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author Soodeh Mahdian
Maryam Shahhoseini
Ashraf Moini
author_facet Soodeh Mahdian
Maryam Shahhoseini
Ashraf Moini
author_sort Soodeh Mahdian
collection DOAJ
description Coronavirus disease 2019 (COVID-19) prevalence has caused many problems in society and disrupted manyregular aspects of life. COVID-19 contains major structural proteins that among them, S protein can promotefusion of the viral and cellular membranes and facilitate the entry of coronavirus into the host cells. Basigin(BSG) is one of the most important receptors for COVID-19 that mediates its entry to host cells. Also, Basiginhas an important role in male and female reproduction. Basigin is expressed in the uterus and plays animportant role during embryo implantation and needed for successful implantation. Therefore, disruption orinhibition of Basigin causes to a weakness in embryo implantation. Therefore, if a woman or a man is infectedwith COVID-19, it is recommended that they do not attempt to conception until their treatment is complete. Itis also recommended tests for COVID-19 be performed on infertile couples before using assisted reproductivetechnology (ART).
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spelling doaj.art-c3bc7782c68f4192b63b900a1c67f28e2022-12-22T03:00:39ZengRoyan Institute (ACECR), TehranInternational Journal of Fertility and Sterility2008-076X2008-07782020-10-0114326226310.22074/ijfs.2020.13470245674COVID-19 Mediated by Basigin Can Affect Male and Female FertilitySoodeh Mahdian0Maryam Shahhoseini1Ashraf Moini2Department of Cellular and Molecular Biology, Faculty of Biological Sciences, North Tehran Branch, Islamic Azad University, Tehran, IranReproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranDepartment of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranCoronavirus disease 2019 (COVID-19) prevalence has caused many problems in society and disrupted manyregular aspects of life. COVID-19 contains major structural proteins that among them, S protein can promotefusion of the viral and cellular membranes and facilitate the entry of coronavirus into the host cells. Basigin(BSG) is one of the most important receptors for COVID-19 that mediates its entry to host cells. Also, Basiginhas an important role in male and female reproduction. Basigin is expressed in the uterus and plays animportant role during embryo implantation and needed for successful implantation. Therefore, disruption orinhibition of Basigin causes to a weakness in embryo implantation. Therefore, if a woman or a man is infectedwith COVID-19, it is recommended that they do not attempt to conception until their treatment is complete. Itis also recommended tests for COVID-19 be performed on infertile couples before using assisted reproductivetechnology (ART).http://www.ijfs.ir/article_45674_f571c3e965f0662181f09336570aec5a.pdfbasigincd147covid-19fertility
spellingShingle Soodeh Mahdian
Maryam Shahhoseini
Ashraf Moini
COVID-19 Mediated by Basigin Can Affect Male and Female Fertility
International Journal of Fertility and Sterility
basigin
cd147
covid-19
fertility
title COVID-19 Mediated by Basigin Can Affect Male and Female Fertility
title_full COVID-19 Mediated by Basigin Can Affect Male and Female Fertility
title_fullStr COVID-19 Mediated by Basigin Can Affect Male and Female Fertility
title_full_unstemmed COVID-19 Mediated by Basigin Can Affect Male and Female Fertility
title_short COVID-19 Mediated by Basigin Can Affect Male and Female Fertility
title_sort covid 19 mediated by basigin can affect male and female fertility
topic basigin
cd147
covid-19
fertility
url http://www.ijfs.ir/article_45674_f571c3e965f0662181f09336570aec5a.pdf
work_keys_str_mv AT soodehmahdian covid19mediatedbybasigincanaffectmaleandfemalefertility
AT maryamshahhoseini covid19mediatedbybasigincanaffectmaleandfemalefertility
AT ashrafmoini covid19mediatedbybasigincanaffectmaleandfemalefertility