Pain-Relieving Effects of Shockwave Therapy for Ledderhose Disease: An Ultrasound-Based Study of an Unusual Bilateral Case

Ledderhose disease (LD, or plantar fibromatosis) is a rare, nodular, hyperproliferative condition affecting the plantar aponeurosis of the foot. At present, several conservative, non-surgical treatments have been documented, although with various degrees of success, with little evidence in the liter...

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Main Authors: Federica Fulceri, Larisa Ryskalin, Gabriele Morucci, Francesco Busoni, Paola Soldani, Marco Gesi
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/14/2/169
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author Federica Fulceri
Larisa Ryskalin
Gabriele Morucci
Francesco Busoni
Paola Soldani
Marco Gesi
author_facet Federica Fulceri
Larisa Ryskalin
Gabriele Morucci
Francesco Busoni
Paola Soldani
Marco Gesi
author_sort Federica Fulceri
collection DOAJ
description Ledderhose disease (LD, or plantar fibromatosis) is a rare, nodular, hyperproliferative condition affecting the plantar aponeurosis of the foot. At present, several conservative, non-surgical treatments have been documented, although with various degrees of success, with little evidence in the literature supporting their efficacy. In this scenario, extracorporeal shock wave therapy (ESWT) has emerged as a safe, effective, and less invasive approach for the successful treatment of several refractory musculoskeletal conditions and soft tissue injuries. Again, recent experimental evidence has shown that ESWT can exert beneficial effects on different fibroproliferative diseases, including Dupuytren’s and Peyronie’s disease. In contrast, the literature regarding the use of ESWT for LD is extremely limited, and no optimal application parameters have been defined to ensure its effectiveness for this disease. Therefore, in the present paper, we report a case of a 48-year-old male patient who developed bilateral foot LD, which was successfully treated with a novel ESWT protocol of treatment consisting of three sessions at 1-week intervals, with 2000 impulses at 5 Hz with an energy flux density of 0.20 mJ/mm<sup>2</sup>. Our data show that this ESWT treatment protocol was effective in completely relieving pain, restoring full functional activity, and thus, greatly improving the patient’s quality of life.
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spelling doaj.art-c3c041a6651948b388b3e1ecf04bcc922024-02-23T15:24:31ZengMDPI AGLife2075-17292024-01-0114216910.3390/life14020169Pain-Relieving Effects of Shockwave Therapy for Ledderhose Disease: An Ultrasound-Based Study of an Unusual Bilateral CaseFederica Fulceri0Larisa Ryskalin1Gabriele Morucci2Francesco Busoni3Paola Soldani4Marco Gesi5Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, ItalyDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, ItalyDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, ItalyCenter for Rehabilitative Medicine “Sport and Anatomy”, University of Pisa, 56121 Pisa, ItalyDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, ItalyDepartment of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, ItalyLedderhose disease (LD, or plantar fibromatosis) is a rare, nodular, hyperproliferative condition affecting the plantar aponeurosis of the foot. At present, several conservative, non-surgical treatments have been documented, although with various degrees of success, with little evidence in the literature supporting their efficacy. In this scenario, extracorporeal shock wave therapy (ESWT) has emerged as a safe, effective, and less invasive approach for the successful treatment of several refractory musculoskeletal conditions and soft tissue injuries. Again, recent experimental evidence has shown that ESWT can exert beneficial effects on different fibroproliferative diseases, including Dupuytren’s and Peyronie’s disease. In contrast, the literature regarding the use of ESWT for LD is extremely limited, and no optimal application parameters have been defined to ensure its effectiveness for this disease. Therefore, in the present paper, we report a case of a 48-year-old male patient who developed bilateral foot LD, which was successfully treated with a novel ESWT protocol of treatment consisting of three sessions at 1-week intervals, with 2000 impulses at 5 Hz with an energy flux density of 0.20 mJ/mm<sup>2</sup>. Our data show that this ESWT treatment protocol was effective in completely relieving pain, restoring full functional activity, and thus, greatly improving the patient’s quality of life.https://www.mdpi.com/2075-1729/14/2/169extracorporeal shock wave therapyplantar fibromatosisLedderhose diseasebenign diseasehyperproliferationplantar fascia
spellingShingle Federica Fulceri
Larisa Ryskalin
Gabriele Morucci
Francesco Busoni
Paola Soldani
Marco Gesi
Pain-Relieving Effects of Shockwave Therapy for Ledderhose Disease: An Ultrasound-Based Study of an Unusual Bilateral Case
Life
extracorporeal shock wave therapy
plantar fibromatosis
Ledderhose disease
benign disease
hyperproliferation
plantar fascia
title Pain-Relieving Effects of Shockwave Therapy for Ledderhose Disease: An Ultrasound-Based Study of an Unusual Bilateral Case
title_full Pain-Relieving Effects of Shockwave Therapy for Ledderhose Disease: An Ultrasound-Based Study of an Unusual Bilateral Case
title_fullStr Pain-Relieving Effects of Shockwave Therapy for Ledderhose Disease: An Ultrasound-Based Study of an Unusual Bilateral Case
title_full_unstemmed Pain-Relieving Effects of Shockwave Therapy for Ledderhose Disease: An Ultrasound-Based Study of an Unusual Bilateral Case
title_short Pain-Relieving Effects of Shockwave Therapy for Ledderhose Disease: An Ultrasound-Based Study of an Unusual Bilateral Case
title_sort pain relieving effects of shockwave therapy for ledderhose disease an ultrasound based study of an unusual bilateral case
topic extracorporeal shock wave therapy
plantar fibromatosis
Ledderhose disease
benign disease
hyperproliferation
plantar fascia
url https://www.mdpi.com/2075-1729/14/2/169
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