Association between Body Mass Index and Gastroesophageal Reflux Symptoms in Nepalese Adult Population. A Single Centered Hospital Based Study

<p class="Default"><strong>Background &amp; Objectives: </strong>Gastroesophageal reflux disease (GERD) is a common disorder, and studies have reported inconsistent association between high BMI and its elevated risk of GERD symptoms. The aim of the present study was t...

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Main Authors: Akhilesh Kumar Kasyap, Shiv Kumar Sah, Sitaram Chaudhary, Ramila Shrestha, Dinesh Shrestha
Format: Article
Language:English
Published: College of Medical Sciences 2015-11-01
Series:Journal of College of Medical Sciences-Nepal
Subjects:
Online Access:http://nepjol.info/index.php/JCMSN/article/view/13672
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author Akhilesh Kumar Kasyap
Shiv Kumar Sah
Sitaram Chaudhary
Ramila Shrestha
Dinesh Shrestha
author_facet Akhilesh Kumar Kasyap
Shiv Kumar Sah
Sitaram Chaudhary
Ramila Shrestha
Dinesh Shrestha
author_sort Akhilesh Kumar Kasyap
collection DOAJ
description <p class="Default"><strong>Background &amp; Objectives: </strong>Gastroesophageal reflux disease (GERD) is a common disorder, and studies have reported inconsistent association between high BMI and its elevated risk of GERD symptoms. The aim of the present study was to estimate the strength of the association between body mass index and reflux symptoms in Nepalese adults.</p><p class="Default"><strong>Materials &amp; Methods: </strong>This was a cross-sectional study conducted at National Academy of Medical Science, Bir Hospital, Kathmandu, Nepal. All patients of age 18 years or above who underwent endoscopy and diagnosed to have esophagitis were recruited for the analysis. Symptoms were identified by using a self-administered validated questionnaire regarding GERD that identify the onset for GERD symptoms and grade the frequency and severity of symptoms experienced over a period of one year. BMI data, the cut off points were based on the WHO classification of overweight and obesity. A BMI value ?25–30 represents overweight and BMI &gt;30 indicates obesity. A BMI value &lt;25 is considered as normal. Severity of erosive esophagitis was graded according to the Los Angeles classification.</p><p class="Default"><strong>Results: </strong>The Among 127 enrolled esophagitis subjects, about 43% were under 20 BMI, 43% overweight and about 24% were obese. Obesity measured by BMI revealed no significant association among age, sex, smoker, alcoholics, hernia and severity grade of esophagitis (p&gt;0.05). Ages with various categories (18-40, &gt;40-60,&gt;60) were significantly associated with the GERD symptoms (P=0.021). We categorize BMI in three categories. A BMI value &lt; 25 (normal), ?25–30 (overweight), and BMI &gt;30 (obesity). Categorical analysis of BMI with GERD symptoms confirmed the absence of any tendency towards an association (p&gt;0.05).</p><p class="Default"><strong>Conclusion: </strong>The tendency of reflux symptoms towards BMI is null, and weight reduction may not be the adequate justifiable for the symptoms therapy.</p><p class="Default">JCMS Nepal. 2015; 11(2):23-26</p>
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spelling doaj.art-c3c52659b945402487ae9c867e8c83f22022-12-21T19:03:31ZengCollege of Medical SciencesJournal of College of Medical Sciences-Nepal2091-06572091-06732015-11-01112232610.3126/jcmsn.v11i2.1367210736Association between Body Mass Index and Gastroesophageal Reflux Symptoms in Nepalese Adult Population. A Single Centered Hospital Based StudyAkhilesh Kumar Kasyap0Shiv Kumar Sah1Sitaram Chaudhary2Ramila Shrestha3Dinesh Shrestha4National Academy of Medical Science, Bir Hospital Mahabaudha, Kathmandu, Department of Medi-cine, Gastroenterology unitLittle Buddha College of Health Science, Minbhawan, Kathmandu, Faculty of Pharmacy, Purbanchal UniversityNational Academy of Medical Science, Bir Hospital Mahabaudha, Kathmandu, Department of Medi-cine, Gastroenterology unitNational Academy of Medical Science, Bir Hospital Mahabaudha, Kathmandu, Department of Medi-cine, Gastroenterology unitNational Academy of Medical Science, Bir Hospital Mahabaudha, Kathmandu, Department of Medi-cine, Gastroenterology unit<p class="Default"><strong>Background &amp; Objectives: </strong>Gastroesophageal reflux disease (GERD) is a common disorder, and studies have reported inconsistent association between high BMI and its elevated risk of GERD symptoms. The aim of the present study was to estimate the strength of the association between body mass index and reflux symptoms in Nepalese adults.</p><p class="Default"><strong>Materials &amp; Methods: </strong>This was a cross-sectional study conducted at National Academy of Medical Science, Bir Hospital, Kathmandu, Nepal. All patients of age 18 years or above who underwent endoscopy and diagnosed to have esophagitis were recruited for the analysis. Symptoms were identified by using a self-administered validated questionnaire regarding GERD that identify the onset for GERD symptoms and grade the frequency and severity of symptoms experienced over a period of one year. BMI data, the cut off points were based on the WHO classification of overweight and obesity. A BMI value ?25–30 represents overweight and BMI &gt;30 indicates obesity. A BMI value &lt;25 is considered as normal. Severity of erosive esophagitis was graded according to the Los Angeles classification.</p><p class="Default"><strong>Results: </strong>The Among 127 enrolled esophagitis subjects, about 43% were under 20 BMI, 43% overweight and about 24% were obese. Obesity measured by BMI revealed no significant association among age, sex, smoker, alcoholics, hernia and severity grade of esophagitis (p&gt;0.05). Ages with various categories (18-40, &gt;40-60,&gt;60) were significantly associated with the GERD symptoms (P=0.021). We categorize BMI in three categories. A BMI value &lt; 25 (normal), ?25–30 (overweight), and BMI &gt;30 (obesity). Categorical analysis of BMI with GERD symptoms confirmed the absence of any tendency towards an association (p&gt;0.05).</p><p class="Default"><strong>Conclusion: </strong>The tendency of reflux symptoms towards BMI is null, and weight reduction may not be the adequate justifiable for the symptoms therapy.</p><p class="Default">JCMS Nepal. 2015; 11(2):23-26</p>http://nepjol.info/index.php/JCMSN/article/view/13672Body mass index, GERD, Obesity
spellingShingle Akhilesh Kumar Kasyap
Shiv Kumar Sah
Sitaram Chaudhary
Ramila Shrestha
Dinesh Shrestha
Association between Body Mass Index and Gastroesophageal Reflux Symptoms in Nepalese Adult Population. A Single Centered Hospital Based Study
Journal of College of Medical Sciences-Nepal
Body mass index, GERD, Obesity
title Association between Body Mass Index and Gastroesophageal Reflux Symptoms in Nepalese Adult Population. A Single Centered Hospital Based Study
title_full Association between Body Mass Index and Gastroesophageal Reflux Symptoms in Nepalese Adult Population. A Single Centered Hospital Based Study
title_fullStr Association between Body Mass Index and Gastroesophageal Reflux Symptoms in Nepalese Adult Population. A Single Centered Hospital Based Study
title_full_unstemmed Association between Body Mass Index and Gastroesophageal Reflux Symptoms in Nepalese Adult Population. A Single Centered Hospital Based Study
title_short Association between Body Mass Index and Gastroesophageal Reflux Symptoms in Nepalese Adult Population. A Single Centered Hospital Based Study
title_sort association between body mass index and gastroesophageal reflux symptoms in nepalese adult population a single centered hospital based study
topic Body mass index, GERD, Obesity
url http://nepjol.info/index.php/JCMSN/article/view/13672
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