Dietary Inflammatory Index and Epithelial Ovarian Cancer in Southern Chinese Women: A Case-Control Study
The association between inflammatory properties of diet and ovarian cancer risk has been investigated in some Western populations. However, little evidence is available from Asian women whose ovarian cancer incidence rates are low and dietary and lifestyle patterns are very different from their West...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2020-11-01
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| Series: | Cancer Control |
| Online Access: | https://doi.org/10.1177/1073274820977203 |
| _version_ | 1797772260494278656 |
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| author | Li Tang PhD Ngoc Minh Pham PhD Andy H. Lee PhD Nitin Shivappa PhD James R. Hébert PhD Jian Zhao PhD Dada Su PhD Colin W. Binns PhD Chunrong Li PhD |
| author_facet | Li Tang PhD Ngoc Minh Pham PhD Andy H. Lee PhD Nitin Shivappa PhD James R. Hébert PhD Jian Zhao PhD Dada Su PhD Colin W. Binns PhD Chunrong Li PhD |
| author_sort | Li Tang PhD |
| collection | DOAJ |
| description | The association between inflammatory properties of diet and ovarian cancer risk has been investigated in some Western populations. However, little evidence is available from Asian women whose ovarian cancer incidence rates are low and dietary and lifestyle patterns are very different from their Western counterparts. We aimed to examine whether more pro-inflammatory diets, as indicated by higher dietary inflammatory index (DII®) scores, are associated with increased odds of epithelial ovarian cancer in southern China. A case-control study was conducted during 2006-2008 in Guangzhou, Guangdong Province. Energy-adjusted DII (E-DII) scores were calculated based on dietary intake assessed by a validated food frequency questionnaire administered to 500 incident epithelial ovarian cancer patients and 500 hospital-based controls. Logistic regression models were used to assess the relationship between E-DII scores and odds of ovarian cancer. Positive associations were observed between higher E-DII scores and ovarian cancer odds, using both continuous DII scores (odds ratio (OR) 1.87; 95% confidence interval (CI) 1.65, 2.13) and by DII tertiles (OR tertile3vs1 7.04, 95% CI: 4.70, 10.54, p for trend < 0.001). Likewise, a more pro-inflammatory diet was associated with a higher chance of serous and mucinous ovarian tumors. Our results suggest that a pro-inflammatory diet was associated with increased odds of developing epithelial ovarian cancer in southern Chinese women. The findings add to epidemiological evidence for the role of dietary inflammatory potential in ovarian cancer development. |
| first_indexed | 2024-03-12T21:48:35Z |
| format | Article |
| id | doaj.art-c3c8ba28a25d4976a5632589d85ab606 |
| institution | Directory Open Access Journal |
| issn | 1073-2748 |
| language | English |
| last_indexed | 2024-03-12T21:48:35Z |
| publishDate | 2020-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Cancer Control |
| spelling | doaj.art-c3c8ba28a25d4976a5632589d85ab6062023-07-26T07:05:01ZengSAGE PublishingCancer Control1073-27482020-11-012710.1177/1073274820977203Dietary Inflammatory Index and Epithelial Ovarian Cancer in Southern Chinese Women: A Case-Control StudyLi Tang PhD0Ngoc Minh Pham PhD1Andy H. Lee PhD2Nitin Shivappa PhD3James R. Hébert PhD4Jian Zhao PhD5Dada Su PhD6Colin W. Binns PhD7Chunrong Li PhD8 Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China Department of Epidemiology, Faculty of Public Health, Thai Nguyen University of Medicine and Pharmacy, Thai Nguyen City, Thai Nguyen Province, Vietnam School of Public Health, Curtin University, Bentley, Perth, Western Australia, Australia Department of Nutrition, Connecting Health Innovations LLC, Columbia, SC, USA Department of Nutrition, Connecting Health Innovations LLC, Columbia, SC, USA MRC Integrative Epidemiology Unit, NIHR Bristol Biomedical Research Centre, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol, UK School of Public Health, Curtin University, Bentley, Perth, Western Australia, Australia School of Public Health, Curtin University, Bentley, Perth, Western Australia, Australia Chengdu Women’s and Children’s Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, ChinaThe association between inflammatory properties of diet and ovarian cancer risk has been investigated in some Western populations. However, little evidence is available from Asian women whose ovarian cancer incidence rates are low and dietary and lifestyle patterns are very different from their Western counterparts. We aimed to examine whether more pro-inflammatory diets, as indicated by higher dietary inflammatory index (DII®) scores, are associated with increased odds of epithelial ovarian cancer in southern China. A case-control study was conducted during 2006-2008 in Guangzhou, Guangdong Province. Energy-adjusted DII (E-DII) scores were calculated based on dietary intake assessed by a validated food frequency questionnaire administered to 500 incident epithelial ovarian cancer patients and 500 hospital-based controls. Logistic regression models were used to assess the relationship between E-DII scores and odds of ovarian cancer. Positive associations were observed between higher E-DII scores and ovarian cancer odds, using both continuous DII scores (odds ratio (OR) 1.87; 95% confidence interval (CI) 1.65, 2.13) and by DII tertiles (OR tertile3vs1 7.04, 95% CI: 4.70, 10.54, p for trend < 0.001). Likewise, a more pro-inflammatory diet was associated with a higher chance of serous and mucinous ovarian tumors. Our results suggest that a pro-inflammatory diet was associated with increased odds of developing epithelial ovarian cancer in southern Chinese women. The findings add to epidemiological evidence for the role of dietary inflammatory potential in ovarian cancer development.https://doi.org/10.1177/1073274820977203 |
| spellingShingle | Li Tang PhD Ngoc Minh Pham PhD Andy H. Lee PhD Nitin Shivappa PhD James R. Hébert PhD Jian Zhao PhD Dada Su PhD Colin W. Binns PhD Chunrong Li PhD Dietary Inflammatory Index and Epithelial Ovarian Cancer in Southern Chinese Women: A Case-Control Study Cancer Control |
| title | Dietary Inflammatory Index and Epithelial Ovarian Cancer in Southern Chinese Women: A Case-Control Study |
| title_full | Dietary Inflammatory Index and Epithelial Ovarian Cancer in Southern Chinese Women: A Case-Control Study |
| title_fullStr | Dietary Inflammatory Index and Epithelial Ovarian Cancer in Southern Chinese Women: A Case-Control Study |
| title_full_unstemmed | Dietary Inflammatory Index and Epithelial Ovarian Cancer in Southern Chinese Women: A Case-Control Study |
| title_short | Dietary Inflammatory Index and Epithelial Ovarian Cancer in Southern Chinese Women: A Case-Control Study |
| title_sort | dietary inflammatory index and epithelial ovarian cancer in southern chinese women a case control study |
| url | https://doi.org/10.1177/1073274820977203 |
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