Mutant Huntingtin Does Not Affect the Intrinsic Phenotype of Human Huntington's Disease T Lymphocytes.

Huntington's disease is a fatal neurodegenerative condition caused by a CAG repeat expansion in the huntingtin gene. The peripheral innate immune system is dysregulated in Huntington's disease and may contribute to its pathogenesis. However, it is not clear whether or to what extent the ad...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: James R C Miller, Ulrike Träger, Ralph Andre, Sarah J Tabrizi
التنسيق: مقال
اللغة:English
منشور في: Public Library of Science (PLoS) 2015-01-01
سلاسل:PLoS ONE
الوصول للمادة أونلاين:http://europepmc.org/articles/PMC4631523?pdf=render