CipA mediates complement resistance of Acinetobacter baumannii by formation of a factor I-dependent quadripartite assemblage

CipA mediates complement resistance of Acinetobacter baumannii by formation of a factor I-dependent quadripartite assemblage

Multidrug-resistant Acinetobacter baumannii is known to be one of the leading pathogens that cause severe nosocomial infections. To overcome eradication by the innate immune system during infection, A. baumannii developed a number of immune evasion strategies. Previously, we identified CipA as a pla...

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Bibliographic Details
Main Authors: Julia I. Ries, Marie Heß, Noura Nouri, Thomas A. Wichelhaus, Stephan Göttig, Franco H. Falcone, Peter Kraiczy
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
Acinetobacter baumannii
immune evasion
innate immunity
complement
serum resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.942482/full

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