Cytotoxic CD8<sup>+</sup> T Cells Are Involved in the Thrombo-Inflammatory Response during First-Diagnosed Atrial Fibrillation

Cytotoxic CD8<sup>+</sup> T Cells Are Involved in the Thrombo-Inflammatory Response during First-Diagnosed Atrial Fibrillation

Background: Atrial myopathy and atrial fibrillation (AF) accompany thrombo-inflammation. This facilitates disease progression and promotes major adverse cardiovascular events (MACEs). Thrombin receptor (protease-activated receptor 1, PAR1) signalling is central in mediating thrombo-inflammation. We...

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Bibliographic Details
Main Authors: Julian Friebel, Marco Witkowski, Max Wegner, Leon Blöbaum, Stella Lammel, Philipp-Alexander Schencke, Kai Jakobs, Marianna Puccini, Daniela Reißner, Daniel Steffens, Verena Moos, Heinz-Peter Schutheiss, Ulf Landmesser, Ursula Rauch
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
atrial fibrillation
atrial myopathy
thrombo-inflammation
thrombin
protease-activated receptor
PAR1
Online Access:https://www.mdpi.com/2073-4409/12/1/141

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